Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer Patients

Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04762914

Enrollment

Registered

2021-02-21

Start date

2018-09-01

Completion date

2019-12-31

Last updated

2021-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer

Keywords

Prehabilitation

Brief summary

Quality Improvement Project to evaluate how prehabilitation can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Detailed description

The aim was to evaluate how prehabilitation (PH) can be incorporated into our colorectal cancer pathway and assess its clinical benefits. Patients underwent PH (exercise, nutrition and psychological support) before resection of colorectal carcinoma in a DGH over fourteen months. Patients were matched by operation, age, sex and ASA to non-prehabilitation (NPH) patients using a prospectively maintained database. Length of stay (LoS) and complication rate and 90-day readmission rates were compared using Wilcoxon and McNemar's methods. Prehabilitation significantly improved peak VO2 and AT. This corresponds to a reduction in predicted 30-day mortality. Despite a higher Charlson index LoS was unchanged suggesting prehabilitation may permit safe resection in comorbid patients.

Interventions

OTHERPrehabilitation

Prehabilitation is a multimodal and multidisciplinary person-centred perioperative approach involving supervised exercise training, nutritional education, management of polypharmacy and psychological advice.

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults over the age of 18 who had prehabilitation for colorectal cancer

Exclusion criteria

* Children * Patients who had prehabilitation but not for colorectal cancer

Design outcomes

Primary

Measure	Time frame	Description
Length of stay	From date of operation to date of discharge in number of days over a 90 day follow up period	Time spent in hospital
Complication rate	Follow up over a period of 90 days following operation	All Clavien-Dindo complications

Secondary

Measure	Time frame	Description
Anaerobic threshold	CPET performed before prehabilitation and after prehabilitation (median of 36 days)	Measured by looking at CPET results pre- and post- prehab

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026