Infertility, Male
Conditions
Keywords
Male infertility, Semen quality, Lifestyle intervention
Brief summary
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment. The primary endpoint is to increase the total amount of motile sperm in male patients undergoing fertility treatment
Interventions
DIETARY_SUPPLEMENTLifestyle
Lifestyle intervention i.e. diet, exercise, smoking cessation, alcohol limitations, dietary supplementation
Sponsors
Peter Humaidan
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Men of couples who are about to start 2nd or 3rd fertility treatment * \> 18 years old * Sperm concentration between 2-40 mill./ml
Exclusion criteria
* Use of testicular sperm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Increase in the total amount of motil sperm in male patients undergoing fertility treatment | 90 days | Change in classical sperm parameters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in DNA fragmentation index (DFI) | 90 days | DFI is measured by Comet Assay |
| Changes in parameters for metabolic syndrome | 90 days | Weight in kilograms |
| Change in plasma lipids | 90 days | Plasma lipids i.e. Total cholesterol, high density lipoprotein, low density lipoprotein and triglycerides |
Countries
Denmark
Outcome results
None listed