Critical Care, Emergencies, Hypotension and Shock, Wounds and Injuries
Conditions
Keywords
Transportation of Patients, Wounds and Injuries, Emergencies, Critical Care
Brief summary
Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality. Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes. Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies. With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome
Interventions
Antifibrinolytics, analgesics, sedatives, neuromuscular blocking agents
Resuscitative technique for exsanguinating traumas
Transfuion of transported blood products for exsanguinating traumas
Stay and play strategy vs scoop and run
Prehospital thorax/abdomen extended focused assessment sonography for trauma
Sponsors
Study design
Eligibility
Inclusion criteria
* Age \> 18 years * Witnessed traumatic event managed by HEMS * Shock at first evaluation (Systolic blood pressure \< 90 mmHg) * Suspect or obvious ongoing haemorrage
Exclusion criteria
* Patients in cardiac arrest at HEMS arrival in which resuscitation is not started or interrupted by HEMS crew
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30 days mortality | 30 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| survival from prehospital to hospital admmission | 1 day | — |
| Hospital length of stay | 6 months | — |
| Blood products transfused during the first 24 hours after hospital admission | 24 hours | — |
| Transport time | 24 hours | time from dispatch to hospital admission (if any) |
Countries
Italy