Hypogonadism; Ovarian
Conditions
Brief summary
Cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population
Detailed description
In this study, we conduct a cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population. Age-matched non-HIV infected MSM group will be used as comparison group. We will also determine the risk factors associated with male hypogonadism (age, duration of HIV infection, comorbidities, BMI, ART use). Correlation will be made between serum testosterone levels and sexual function, vitality, exercise capacity, mood, and bone mineral density.
Interventions
DIAGNOSTIC_TESTTestosterone
Serum total testosterone and free testosterone level
Sponsors
National Taiwan University Hospital
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
20 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* HIV-infected men who have sex with men * HIV non-infected men
Exclusion criteria
* Use of testosterone supplement, anabolic steroid in the past one year. * History of pituitary , adrenal or gonad diseases * History of pituitary surgery or radiation therapy * History of systemic chemotherapy * Active opportunistic infection under treatment * Cancer * Severe hepatic, renal or cardiac impairment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Symptoms of androgen deficiency | 2021-2030 | We use the score of Androgen Deficiency in Aging Males (ADAM) questionnaire to study the prevalence of hypogonadism in HIV-infected MSM population |
| Serum free testosterone | 2021-2030 | We use serum free testosterone to study the prevalence of hypogonadism in HIV-infected MSM population |
Countries
Taiwan
Contacts
Primary ContactShyang-Rong Shih, Ph.D.
Outcome results
None listed