Diabetes Mellitus, Type 2
Conditions
Keywords
Type II diabetes, cardiometabolic risk, high-intensity interval training
Brief summary
Background: Physical activity is known to modify some of the diabetes risk factors; however, solid evidence is still needed to precisely know the optimum form of training best fits the individual needs of type II diabetic (T2D) patients.
Detailed description
Objectives: the purpose of this study was to compare between high intensity interval training (HIIT) and moderate-intensity interval training (MIIT) effect on functional capacity (as a cardiorespiratory parameter), and on glucose control and glycated hemoglobin (HbA1C) (as metabolic parameters) in T2D patients, and to test exercise acceptability within these patients. Methods: 60 participants had participated in this study. Their ages ranged from 45 to 65 years. They were randomized into two equal groups (30/group); group (A) did HIIT and group (B) did MIIT. Both groups received 12 weeks of training. Measurements for six minute walking distance (6MWD), fasting blood glucose (FBG), and HbA1C levels were done before and after the study. Physical activity enjoyment scale (PACES) were filled by the patients by the end of the study; testing exercise enjoyment.
Interventions
BEHAVIORALHigh-intensity interval training
High-intensity interval training is a form of intermittent training using relatively high exercise intensity
BEHAVIORALModerate intensity interval training
Moderate intensity interval training is a form of intermittent training using moderate exercise intensity
Sponsors
Kasr El Aini Hospital
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
ALL
Age
45 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Controlled type 2 diabetic patients who were clinically stable for at least 3 months before entering the study, * Aged 45-65 years * Non-smokers * body mass index (BMI) ranged between 20 to 39.9 Kg/m2 * Fasting blood glucose ranged from (126-160) mg/dl * Sedentary lifestyle who didn't engage in physical activity for more than half an hour/ day for at least one month before entering the study.
Exclusion criteria
* unstable medical condition * smoker, recent surgery * Body mass index is more than 39.9 kg/m2 or less than 20 kg/m2 * Any known musculoskeletal or neurological conditions that might interfere with the execution or the assessment of the exercise
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| six minute walking distance (in meters) | 12 weeks | represent aerobic capacity (distance walked in 6 min) |
| Glycated Hemoglobin (HbA1C) | 12 weeks | Representing glucose control over 120 days |
| Fasting blood glucose | 12 weeks | Representing glucose level after 9 hours fasting |
| Exercise enjoyment and acceptability | 12 weeks | The Physical Activity Enjoyment Scale (PACES) score, out of 119. It is an 18-item scale that assesses enjoyment for physical activity by asking participants to rate how you feel at the moment about the physical activity you have been doing using a 7-point bipolar Likert scale, from 1 (I enjoy it) to 7 (I hate it). Eleven items were negatively worded and seven items were positively worded. After reverse scoring the 11negatively worded items, an overall enjoyment for physical activity score is determined by summing the items, with a range of 18-126 being possible. Higher scores indicate higher enjoyment. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Adherence rates | 12 weeks | To what extent the patients will adhere to the exercise protocol |
Countries
Egypt
Outcome results
None listed