Comparison of Changes of ONSD Between Groups of Laparoscopic Surgery With and Without Epidural Saline Injection

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04758013

Enrollment

Registered

2021-02-17

Start date

2020-12-16

Completion date

2022-12-16

Last updated

2021-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidural, Optic Nerve Sheath Diameter, Pneumoperitoneum

Keywords

ONSD, pneumoperitoneum, epidural

Brief summary

This study targets patients undergoing laparoscopic gastric cancer surgery. The investigators would like to compare two factors that influence intracranial pressure through optic nerve sheath diameter measurement. First factor is intraperitoneal pressure. Second factor is epidural pressure. The investigators divided the patients into three groups. Group A is patients with laparoscopic gastric surgery who received epidural injection through an thoracic epidural catheter. Group B is patients with laparoscopic gastric surgery who don't received epidural injection through an thoracic epidural catheter. Group C is patients with open gastric surgery.

Interventions

PROCEDUREEpidural injection through thoracic epidural catheter

The investigators inject drugs through a catheter inserted into the thoracic epidural space to control pain after surgery in patients undergoing gastric surgery by laparoscopy.

PROCEDUREWithout epidural injection

The investigators don't epidural injection to find out the effect of only inter-abdominal pressure on intracranial pressure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Gastric surgery due to cancer

Exclusion criteria

* Coagulopathy * Infection * Previous history of thoracic spine surgery * Ophthalmic diseases * History of increased Intracranial Pressure

Design outcomes

Primary

Measure	Time frame	Description
T0 : Optic nerve sheath diameter	10 minutes after anesthesia induction	The investigator measures Optic nerve sheath diameter by ultrasonography.
T1 : Optic nerve sheath diameter	10min after entering the laparoscope	The investigator measures Optic nerve sheath diameter.
T2 : Optic nerve sheath diameter	1hour after entering the laparoscope	The investigator measures Optic nerve sheath diameter.
T3 : Optic nerve sheath diameter	10min after the laparoscopy comes out	The investigator measures Optic nerve sheath diameter.

Countries

South Korea

Contacts

Primary ContactJiSeob Kim

demiandew@naver.com01027487480

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026