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Performance Indicators of the SARC-F Questionnaire in Acute Care

Performance Indicators of the SARC-F Questionnaire in Acute Care

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04757454
Acronym
SARC-F-CHUB
Enrollment
105
Registered
2021-02-17
Start date
2019-09-01
Completion date
2020-11-11
Last updated
2021-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Old Age; Debility, Sarcopenia, Sensitivity

Brief summary

The study applies the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire in older patients hospitalized in an acute care geriatric unit and aims to determine its performance indicators to screen for sarcopenia according to the revised European Consensus on definition and diagnosis (EWGSOP2) within this population

Detailed description

Sarcopenia is an age-related disease associated with health adverse outcomes, i.e. higher risk of mobility limitation, falls, fractures, mortality, and lower quality of life. The European Working Group on Sarcopenia has recently revisited one of the widely used most acknowledged definitions and launched the revised European consensus on definition and diagnosis (EWGSOP2) (4). Applying the EWGSOP2 is a three-tier process: first, screening by the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire; second, diagnosis by low muscle strength, and low muscle mass; third, severity grading by low muscle function. The EWGSOP2 recommends the assessment of sarcopenia in every population, both in community-dwelling and acute care older patients. However, the evidence about the performance indicators of the SARC-F questionnaire to screen for sarcopenia in acute patients admitted to an acute care unit is really limited.

Interventions

DIAGNOSTIC_TEST5-item SARC-F questionnaire

Administration of the 5-item SARC-F questionnaire in patients admitted to an acute care unit

Sponsors

Brugmann University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients aged 65 and over * Hospitalized in an acute care geriatric unit due to acute health issues or acute medical conditions * With SARC-F, hand-grip strength and dual-energy X-ray absorptiometry administered during hospital admission

Exclusion criteria

* SARC-F unavailable * Unwilling to collaborate in the sarcopenia assessment * Unwilling to sign the informed consent

Design outcomes

Primary

MeasureTime frameDescription
Sensitivity of the SARC-F questionnaire as screening method compared to the gold standard, which is the revised European consensus on definition and diagnosisSeptember 2019-November 2020Sensitivity, measured as a percentage (%)
Specificity of the SARC-F questionnaire as a screening method, compared to the gold standard which is the revised European Consensus on definition and diagnosis of sarcopenia (EWGSOP2)September 2019-November 2020Specificity, measured as a percentage (%)
Overall concordance agreement between the SARC-F questionnaire as a screening method and the gold standard method, which is the EWGSOP2September 2019-November 2020Cohen-kappa coefficient, measured as a percentage (%)

Secondary

MeasureTime frameDescription
Health adverse outcomes based on the screening and diagnosis of sarcopenia as recommended by the EWGSOP21-year follow-upMortality risk

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026