Myocardial Infarction
Conditions
Keywords
stimulation in cardiac scar area
Brief summary
Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters. However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility. However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.
Interventions
DEVICENOGA TM probe
Each subject will be his own witness since the linear local shortening (LLS) will be measured successively in all patients before, then after stimulation of the scar zone (comparison of LLS measured in sinus rhythm then during stimulation in the scar zone for each patient. Each subject being his own witness and the two recordings being made a few minutes apart, during the same procedure.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
\- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation) OR * patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation) * Affiliated with a social protection scheme * Having signed an informed consent
Exclusion criteria
* Contraindication or non-indication for ventricular tachycardia ablation * Women who are pregnant or of childbearing age and without contraception, breastfeeding women * Patients without ischemic heart disease * Patients under guardianship, curatorship or legal protection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evolution of LLS (linear local shortening) via the NOGATM system in percentage | 1month | Study the change in percentage of LLS during stimulation in a post-infarction scar zone identified by voltage mapping of the left ventricle with the NOGA system, compared to LLS in the same zone measured in atrial stimulation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Evolution of global systolic function: left ventricular ejection fraction | 1month | Compare the left ventricular ejection fraction (in percentage) during stimulation in a scar area compared to a normal rhythm |
| Evolution of the global systolic function: integral time velocity under aortic Translation results Evolution of the global systolic function: integral time velocity under aortic | 1month | Compare the integral time velocity under aortic (in centimeter) during stimulation in a scar area compared to a normal rhythm |
| Evolution of the global systolic function: strain longitudinal global | 1month | Compare the strain longitudinal global(in percentage) during stimulation in a scar area compared to a normal rhythm |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORAnne ROLLIN, MD
University Hospital, Toulouse
Outcome results
None listed