Osteoblast, Vascular Calcification
Conditions
Keywords
osteoblast, Vascular Calcification, vascular smooth muscle cell, Cardiac valve calcification, Valvular interstitial cell, bone tissue
Brief summary
Although it is now established that calcification process result from the joint and coordinated action of different cell types, many areas of shadow remain regarding the spatio-temporal implementation of these events. Highlighting these processes requires additional research to consider new approaches to clinical management of patients with such conditions. It is in this context that the investigators need to use residual human tissue fragments resulting from surgery which are not intended to be used for clinical-biological management of patients. The use of these pseudonymised human tissues will allow the investigators to conduct in vitro cell culture experiences.
Interventions
None listed
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie * patients who will be beforehand informed * patients who will not be opposed to this study.
Exclusion criteria
* HIV and hepatitis positive patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success in establishment of Cell Culture Systems from discarded surgery specimens | 5 years | Success in establishment of Cell Culture Systems from discarded surgery specimens |
Countries
France
Contacts
CONTACTRomuald Mentaverri, Pr
Outcome results
None listed