Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04753450

Acronym

DIASEM

Enrollment

Registered

2021-02-15

Start date

2021-03-09

Completion date

2022-10-19

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging, Assessment, Self, Muscle Atrophy, Ultrasound Therapy; Complications

Brief summary

The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for muscle mass. For the moment, validation of prediction equations in older adults with varying function and health is lacking. The study aims to evaluate correlation of muscle mass between 3D muscle mass measurement and DXA, in order to dispense with the prediction equation.

Detailed description

Older patients who agree to participate to the study will undergo 3D ultrasound muscle mass measurement, 2D panoramic mode muscle mass measurement and biphotonic X-ray absorptiometry assessment. Correlation analysis will be done with the different measurement.

Interventions

OTHERNo intervention

No intervention

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

75 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients over 75 years old * Osteoporosis diagnosis confirmed by Dual-energy X-ray Absorptiometry

Exclusion criteria

* Neurocognitive disorders preventing the expression of informed consent * Patients who cannot undergo an examination in a static position * Lack of a measurement site (muscle resection or amputation) * Any state of dehydration or water inflation * Patient with legal protection measure

Design outcomes

Primary

Measure	Time frame	Description
3D Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results	1 week	Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results

Secondary

Measure	Time frame	Description
2D correlation between muscle volume measured by 2D ultrasound and standard method : DXA results	1 week	Correlation between muscle volume measured by 2D ultrasound and standard method : DXA results

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026