Covid19, SARS-CoV Infection
Conditions
Keywords
COVID-19, chitotriosidase, SARS-CoV Infection
Brief summary
The aim of the cohort prospective observational study is to define the major factors influencing the course of COVID-19 infections and its prognosis in hospitalised patients. The investigators plan to include 300 patients hospitalised with COVID-19 infection. The phone contacts with patients are due after 90 and 180 days after discharge.
Interventions
DIAGNOSTIC_TESTChitotriosidase activity
The chitotriosidase activity will be measured in all the subjects
Sponsors
I.M. Sechenov First Moscow State Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hospitalisation with COVID-19
Exclusion criteria
* History of hospitalisation with COVID-19 infection * Discharge from the hospital before the end of the treatment course * Transfer to another hospital
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Need in biological therapy or/and respiratory support | Up to 1 month | The primary endpoint is the need in biological therapy or/and respiratory support including noninvasive ventilation during hospital stay |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of days spent in hospital | Up to 1 month | The investigators plan to assess the overall length of hospitalisation due to COVID-19 infection as an outcome measure |
| All-cause death | 90 days | To assess the all-cause death 90 days after discharge |
Countries
Russia
Outcome results
None listed