Impact of Maternal COVID-19 Vaccines on Breast Milk

Impact of Maternal COVID-19 Vaccination on Breast Milk Antibodies, Milk Bioactive Compounds and Maternal-child Health

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04751734

Acronym

MilkCorona

Enrollment

120

Registered

2021-02-12

Start date

2021-01-16

Completion date

2023-12-31

Last updated

2024-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 Vaccines

Keywords

breast milk, microbiota, metabolites, immune compounds, growth and development

Brief summary

prospective multicenter study The main aim is to study the impact of maternal COVID-19 vaccination on breast milk immune, microbiological, and metabolic profile.

Interventions

BIOLOGICALCovid vaccines

women within Priority groups for coronavirus (COVID-19) vaccination

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Priority groups for coronavirus (COVID-19) vaccination (health and social care workers) following breastfeeding practices and receiving vaccines.

Exclusion criteria

* cessation of breastfeeding and vaccine side-effects requiring specific treatment and/or hospitalization.

Design outcomes

Primary

Measure	Time frame	Description
Antibodies	1st year	presence and levels of antibodies

Secondary

Measure	Time frame	Description
breast milk bioactive composition	1st year	immune profile (cytokines and growth factors, immunoglobulins)
infant microbiota	1st year	infant microbiota composition and diversity
infant growth and development	1st year	z-scores growth curves

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 18, 2026