Bowel Obstruction Small
Conditions
Keywords
Small Bowel Obstruction
Brief summary
Small bowel obstruction (SBO) is a common and potentially life-threatening acute surgical condition. A minority of patients present with a clear indication for urgent surgical intervention, either on the basis of clinical or radiological assessment (clinical signs of peritonitis/sepsis; suspicion of bowel ischaemia; closed loop obstructions; irreducible herniae etc.). However, the optimal management of the remaining patients, the majority of whom present with SBO caused by abdominal adhesions, remains a topic of international debate with practice varying in different healthcare systems. This multicentre, prospective, observational study aims to describe the current management of patients admitted with SBO in 6 acute hospitals (Bispebjerg, Herlev, Hillerød, Hvidovre, Køge, Slagelse) on the island of Sjælland, Denmark, which accounts for a 1/3 of the total Danish population.
Detailed description
This is a prospective, non-interventional observational study of the management and outcomes of patients admitted with SBO in Denmark. Relevant clinicopathological demographics will be retrieved from consenting patients' medical records. An initial analysis will be performed once these patients have reached 90 days follow-up after the start of treatment. The long-term outcomes of treatment will be assessed with further analyses at 1, 3 and 5 years follow-up.
Interventions
None listed
Sponsors
Danish Small Bowel Obstruction Collaborative
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years old * Radiological or clinical diagnosis of mechanical SBO * Admitted to one of the 6 participating centres
Exclusion criteria
* SBO presenting within 30 days of a previous abdominal operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30-day mortality rate | 30 days |
| 30-day morbidity rate | 30 days |
Secondary
| Measure | Time frame |
|---|---|
| To describe the proportion of patients undergoing operative versus non-operative management | From 90 days |
| To determine the success rate of non-operative management in patients with SBO and identify predictors of success/failure | From the start of treatment until 90-days follow-up |
| To determine the incidence and consequence of malnourishment in patients with SBO | 90 days |
| To determine the incidence and consequence of acute kidney injury in patients with SBO | 90 days |
| 90-day mortality rate | 90 days |
Other
| Measure | Time frame |
|---|---|
| To determine the incidence of recurrent SBO at 1-year, 3-year and 5-year follow-up. | Up to 5 years |
Countries
Denmark
Outcome results
None listed