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Work Productivity and Social Activities In Patients With Ankylosing Spondylitis

The Relationship Between The Decreasing Activity, Depression And Quality Of Life In Work Productivity And Social Activities In Ankylosing Spondylitis Patients: A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04749537
Enrollment
200
Registered
2021-02-11
Start date
2019-04-15
Completion date
2020-12-15
Last updated
2021-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis, Work Productivity

Keywords

Spondylitis, Ankylosing, Quality of Life, Employment

Brief summary

The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with demographic data.

Detailed description

For this study, which is planned as a cross-sectional clinical study, 100 patients who were diagnosed with AS between the ages of 18-65 and who applied to the Istanbul Physical Therapy Rehabilitation SUAM Physical Medicine and Rehabilitation Outpatient Clinic between April 15, 2019, and April 15, 2020, and 100 healthy volunteers compatible with age. was included. Demographic data of the participants were recorded. Work productivity and activity reduction questionnaire: general health (WPAI: GH), social role participation questionnaire short form (SRPQ), short form-36 (SF-36), hospital anxiety, and depression scale (HADS), will be evaluated. Besides, if the patient group exists, laboratory results (CRP, erythrocyte sedimentation rate, HLA-B27), and bath ankylosing spondylitis functional index (BASFI), bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis metrology index (BASMI), visual analog scale (VAS) resting, night and activity values were recorded.

Interventions

None listed

Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients with AS diagnosis between the ages of 18-65 * Healthy volunteer individuals between the ages of 18-65 without known musculoskeletal disease

Exclusion criteria

* Those with serious systemic diseases that may interfere with working (respiratory system, cardiovascular system, renal and metabolic diseases) * Those with orthopedic and psychiatric diseases * Those with inflammatory diseases other than known AS * Pregnant * People with disability due to the history of trauma * Those with injury after the operation * Those with diseases that cause neurological sequelae

Design outcomes

Primary

MeasureTime frameDescription
Work Productivity and Activity Impairment Questionnaire: General Health V2.0 (WPAI:GH)One dayWPAI: GH measures health impact and symptom severity impact on work productivity and leave time effectiveness
Social Role Participation Questionnaire (SRPQ)One dayIt is used to evaluate integration into society and activities in social life. It evaluates the level of participation in six social roles in two dimensions: the experienced physical difficulties scale and the role performance satisfaction scale. Participants complete their satisfaction and challenges during their social roles

Secondary

MeasureTime frameDescription
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)One daythe assessment of disease activity in patients with ankylosing spondylitis
Bath Ankylosing Spondylitis Functional Index (BASFI)One daythe assessment of functional status in patients with ankylosing spondylitis
Short Form Health Survey 36 (SF-36)One dayused to evaluate the quality of life
Ankylosing Spondylitis Quality of Life (ASQoL)One dayused to evaluate the quality of life in patients with ankylosing spondylitis
Visual Analogue Scale (VAS)One dayused to evaluate the pain
Bath Ankylosing Spondylitis Metrology Index (BASMI)One daythe assessment of the level of spinal mobility in patients with ankylosing spondylitis
Hospital Anxiety and Depression Scale (HADS)One dayused to determine the risk in terms of anxiety and depression in a patient with a physical illness, and to measure the level and change of severity.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026