Cancer
Conditions
Keywords
MRI
Brief summary
The primary aim of the study is to quantify abdominal motion in order to optimise MR imaging. The study will compare three-motion management strategies a) free-breathing, b) using an abdominal compression belt and c) using MRI-compatible visually guided breath-holds.
Interventions
DEVICECompression belt
The abdominal belt is fastened around the lower abdomen and inflated (like an inner tube) to apply pressure to the belly and reduce the motion associated with respiration (breathing)
OTHERVisual Guided Breath-hold
A small tracer will be place on the lower abdomen that will feedback to a computer screen that will have graphics to show you if the participant is in breath-hold or not.
Sponsors
The Christie NHS Foundation Trust
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Healthy volunteers * 18 years or older, * no MRI contra-indications * must agree to registration as a non-patient in CWP (the local electronic healthcare records system) and have their MRIs read and reviewed for incidental findings by a clinical radiologist Patient Volunteers * undergoing radiotherapy to the abdominal region at the Christie NHS Foundation Trust * Over 18 years of age
Exclusion criteria
* Any contraindications to MRI identified after MRI safety screening including completion of an MRI Safety Screening Form * Unable to tolerate MRI scan * Pregnancy * Colostomy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MRI Motion Management SOP | through study completion, approximately 6 months | Development and implementation of an MRI protocol suitable for organ motion characterisation for the abdomen. Determination of the benefit of motion management strategies for abdominal radiotherapy. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quantification of motion | through study completion, approximately 6 months | Quantification of intra-abdominal inter and intra-fraction motion with and without abdominal compression and visually guided breath holds using MR imaging. Comparative analysis of comparable treatment plans with and without abdominal compression and visually guided breath holds on relevant treatment planning software for PBT and MRL. Development of process to evaluate patient compliance when using a commercial available abdominal compression belt and visually guided breath-hold. |
Countries
United Kingdom
Outcome results
None listed