New Imaging Tools to Explore Impact of Bariatric Surgery on Pancreatic Lesions: PACHIBA- Bariatric Surg

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04746703

Acronym

PACHIBA

Enrollment

Registered

2021-02-10

Start date

2021-02-10

Completion date

2023-09-16

Last updated

2026-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery

Keywords

bariatric surgery, pancreatic parameters

Brief summary

The investigators propose an exploratory study aiming at assessing the impact of surgical bariatric treatment on the improvement of pancreatic lesions detected by MRI. Pancreatic MRI will be performed in severe-obese patients with a planned bariatric surgery, before and 6 months after bariatric surgery. To assess the impact of bariatric surgery on pancreatic Magnetic Resonance Imaging (MRI) parameters in severe-obese patients

Interventions

RADIATIONMagnetic Resonance Imaging

Pancreatic MRI will be performed in severe-obese patients with a planned bariatric surgery, before and 6 months after bariatric surgery.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

The investigators propose an exploratory study aiming at assessing the impact of surgical bariatric treatment on the improvement of pancreatic lesions detected by MRI.

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Adults (aged 18 to 65 years) with a planned for bariatric surgery (sleeve gastrectomy) according to HAS criteria * Patients with severe obesity (BMI≥35)

Exclusion criteria

* Patients with problem of alcohol abuse (previous or current) * Patients with problems of understanding * Patients with previous acute or chronic pancreatitis * Patients with contraindication to MRI (active implantable medical devices, pacemaker, claustrophobia …) * Inability to undergo MRI due to weight excess * Pregnant or breastfeeding woman * Absence of free and informed consent * Non affiliation to a social security regime or CMU (Universal health coverage) * Patient under AME (State medical aid) * Patient deprived of freedom, subject under a legal protective measure * Patients who have already had bariatric surgery Secondary

Design outcomes

Primary

Measure	Time frame	Description
Quantitative MRI parameters	6 months after inclusion	Pancreatic fat content

Secondary

Measure	Time frame	Description
Metabolic and anthropometric parameters before and after bariatric surgery	6 months after inclusion	BMI
lipids parameters	6 months after inclusion	total cholesterol, HDL, LDL, triglycerides

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 14, 2026