NSCLC Stage IV, Brain Metastases
Conditions
Brief summary
The investigators collected the data from the investigators' center between January 2011 and October 2020. The study included all non-small cell lung cancer patients with surgically excised brain metastasis. The investigators analysis the correlation of gene mutation and the disease course.
Detailed description
The investigators collected the data from from the investigators' center between January 2011 and October 2020. The study included all non-small cell lung cancer patients with surgically excised brain metastasis. The investigators analysis the correlation of gene mutation and the disease course. The investigators use Kaplan-Meier regression to analyze the overall survival, and the difference between the groups was calculated using log rank test. Cox proportional hazards method was used to create the regression model and estimate the hazard ratios.
Interventions
PROCEDUREcraniectomy
craniectomy outcomes and survival
Sponsors
National Cheng-Kung University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
\- patients diagnosed with non-small cell lung cancer who underwent craniectomy and subsequent whole brain radiotherapy and associated chemo or target therapy
Exclusion criteria
* patient who did not receive postoperative adjuvant therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative survival | From date of craniectomy until the date of patient deceased or date of last followed medical record, with median follow up around to 20 months |
Countries
Taiwan
Outcome results
None listed