Skip to content

TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda

TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda: Screening, Diagnostics, Risk Factors and Handling of Children Drinking Alcohol

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04743024
Acronym
TREAT C-AUD
Enrollment
7188
Registered
2021-02-08
Start date
2020-12-27
Completion date
2025-07-31
Last updated
2023-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Abuse, Alcohol Dependence, Alcohol Drinking, Alcoholism, Alcohol Use Disorder, Child Abuse, Child Malnutrition, Child Mental Disorder, Child Neglect, Child, Only

Brief summary

The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities. The investigators will focus on the age group 6-13 years overlapping with the recommended age for primary school attendance. The project is approaching the research topic using quantitative and qualitative methods. The TREAT C-AUD research project will therefore document to which degree alcohol drinking is a problem among children in Mbale, Eastern Uganda.

Detailed description

Uganda has as many other sub-Saharan countries high alcohol consumption per capita and traditions for home brewing. The TREAT C-AUD research project, with partners from Makerere University in Uganda, University of Bergen and Norwegian University of Science and Technology in Norway, will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities. The investigators will focus on the age group 6-13 years overlapping with the recommended age for primary school attendance. The project is approaching the research topic from comprehensive perspectives including a large cross-sectional study, interviews with parents and carers, children and stakeholders in the communities, schools and in the health system. The investigators have been including community representatives, expert groups, user groups and stakeholders in the development of screening tools and will do so in interpreting and disseminating the results. The investigators have to take the Covid-19 situation into account both with regard to its effect on the research question at stake and the methods used. The TREAT C-AUD research project will therefore document to which degree alcohol drinking is a problem among children in the communities in Mbale District, Eastern Ugandan. The data collection is capturing cofactors such as other substance use, mental health, parenting, trauma, nutrition and growth. The development of alcohol assessment tools can be used by the health- and school-system for detection and handling of children having problems with alcohol. The investigators will collaborate closely with services in case of identification of children suffering severe harm and adhere to Good Clinical Practice guidelines for ethical conduct, the consent procedure, follow-up and referral.

Interventions

None listed

Sponsors

The Research Council of Norway
CollaboratorOTHER
Makerere University
CollaboratorOTHER
Norwegian University of Science and Technology
CollaboratorOTHER
University of Bergen
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
6 Years to 13 Years
Healthy volunteers
Yes

Inclusion criteria

Care-giver- child pairs * Children 6-13 years * Caregiver of eligible child * Caregiver adult capable of giving informed consent * Living in household for minimum 6 months together

Exclusion criteria

• Caregiver or child not living in household

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of alcohol use disorder using context adapted CRAFFT screening tool2020-2021Period

Secondary

MeasureTime frameDescription
Adult trauma: Stressful Life Events Screening Questionnaire (SLESQ)2020-2021Scored yes (1) or no (0). 14 questions Min: 0 Max 14 The total score is calculated by adding together the score for each of the items where a higher score indicates more stressful live events.
Child mental health: Pediatric symptom checklist (PSC) - child and adolescent version 35 Mental health measures using Pediatric symptom checklist2020-2021PSC (Pediatric symptom checklist) 35 questions. It is scored from 2 (often), 1 (sometimes), to 0 (never). Minimum score= 0, maximum score = 70 The total score is calculated by adding together the score for each of the items where a higher score indicates more impairment.
Carer mental health: Self Reporting questionnaire (SRQ) Mental health measures using Pediatric symptom checklist - child version2020-202120 questions. Scored yes (1) or no (0). The total score is calculated by adding together the score for each of the items where a higher score indicates more symptoms of mental illness. Min: 0, max: 20
Carer substance use: The alcohol use disorder identification test (AUDIT)2020-202110 questions, most reported as increasing frequency. The higher score the more vulnerability to having an alcohol drinking problem. Min: 0, max: 20
Dietary diversity- 24 hour recall, food categories as specified by food and agriculture organization 2010 (ISBN 978-92-5-106749-9)2020-2021A higher score means higher diversity
Food frequency questionnaire2020-2021the most common food items captured as: 0 = No/never, 1. = Yes, less than weekly 2. = 1-3 times/week 3. = 4-6 time/week 4. = daily A higher score means a richer, more diversified diet
Household food security-HIFAS2020-20216 questions on food security recorded as: 0 = No/never 1. = Seldom/rare: less than once per month 2. = Sometimes: 1-2 days last month 3. = Often: 3-10 days/month 4. = Very often/usually: more than 10 days last month A higher score means higher household food insecurity.
Parenting: Alabama Parenting questionnaire short form (APQ - 15)2020-2021The short form includes 15 items scored 0 (never), 1 (almost never), 2 (sometimes), 3 (often), 4 (always) on the five subscales as follows: Involvement (3 qs), Positive Parenting (3 qs), Poor Monitoring/Supervision (3 qs), Inconsistent Discipline (3 qs), Corporal Punishment (3 qs), respectively. No reverse coding necessary when sub-scales reported separately.
Parenting: Conflict Tactic Scale (Original: Straus, 1979, we use: Murray 1995) Version: PARENT-CHILD CONFLICT TACTICS SCALES, FORM CTSPC-CA2020-2021Parent score: 0=no, 1=yes Parent form: Min= 0, max= 22 High score indicates high level of conflict and violence. Child score: 0 = it has not happened in the past year 1. = less than monthly 2. = monthly 3. = weekly 4. =daily Included subscales: Psychological aggression (5 qs), severe assault (4 qs), and very severe assault (4 qs), problems with taking care of child (5 qs) Child form: Min = 0, max = 88 High score indicates high level of conflict and violence.
Child trauma: Child and Adolescent Trauma Screen (CATS)2020-2021Scored yes (1) or no (0). 16 questions, yes/no Min: 0 Max: 16 The total score is calculated by adding together the score for each of the items where a higher score indicates more traumatic events.
Post traumatic stress disease (PTSD) 2-item checklist2020-20212 questions on clinical and psychological symptoms recorded as: 0=Not at all 1. A little bit 2. Moderately 3. Quite a Bit 4. Extremely Min-Max: 0-8 A higher score means higher symptom load.

Other

MeasureTime frameDescription
Urine Etg2020-21Contionuous
Standard U-stix: U-blood, protein, glucose, ketones, nitritt, leukocytes, Ph2020-21Qualitative reading, positive or negative
Other substance use - sections from Global School Based Health surveys2020-2021Not a scale, individual questions measuring frequency and number of units used, measured in days per month and units per month.
Height, in cm, 0.1 nearest cm2020-2021Continuous
Mid upper arm circumference, cm 0.1 nearest cm2020-21Continuous
Weight, in kg, 0.1 nearest kg2020-21Continuous

Countries

Uganda

Contacts

Primary ContactIngunn MS Engebretsen, PhD
ingunn.engebretsen@uib.no+4755588553
Backup ContactAnne-Berit Kolmanskolg, Ms
Anne.Kolmannskog@uib.no+47 55 58 54 39

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026