Skip to content

Task of Acoustic-phonetic Decoding on Anatomic Deficits in Paramedical Assessment of Speech Disorders for Patients Treated for Oral or Oropharyngeal Cancer

Validity of a Task of Acoustic-phonetic Decoding on Anatomic Deficits in Paramedical Assessment of Speech Disorders for Patients Treated for Oral or Oropharyngeal Cancer

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04742998
Acronym
DAPADAF-E
Enrollment
116
Registered
2021-02-08
Start date
2021-10-22
Completion date
2024-10-22
Last updated
2023-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Speech Intelligibility

Keywords

speech deficit, tumor pathologies of the upper aero-digestive tract

Brief summary

The bridging of the gap between speech production and perception by the interlocutor would be made possible by the use of a more suitable and automatic task. An acoustic-phonetic decoding test (or DAP in French, i.e. the production of isolated pseudo-words in repetition or reading), created within the framework of the The French National Cancer Institute (InCA) C2SI project, avoids the effects of cognitive restoration by the interlocutor. An automatic score from the DAP would lead to an overall score per patient, but also to scores specific to each phonetic segment, to be correlated with the analytical scores from each anatomical oropharyngeal segment. The study hypothesis is that the automatic processing of an acoustic-phonetic decoding task during the assessment in current practice is a valid and reliable tool for diagnosing oropharyngeal analytical and dynamic deficits by highlighting deficient linguistic units. The study hypothesis is that the automatic processing of an acoustico-phonetic decoding task during the assessment in current practice is a tool for diagnosing oropharyngeal analytical and dynamic deficits by highlighting deficient linguistic units.

Detailed description

Fifth cancer in terms of incidence in France, tumor pathologies of the upper aero-digestive tract, due to their location, impact the speech abilities of affected subjects. Speech therapy in paramedical clinical assessments consist of two parts. * The analytical part to highlight the anatomical and dynamic deficits of segments involved in speech. * The functional part characterizes the pathophysiological impact by means of an ear assessment. The link between anatomy and functional speech deficit is very close in oncology (the location and the size of the tumor, the structural changes due to the treatment who modify the oropharyngeal dynamics and the mechanisms involved in the production of the speech), but the correlation is weak between functional intelligibility scores and analytical motor scores. Indeed, the perception of speech by a human listener is not a simple recording of the production, but a representation of this production after implementation of individual mechanisms for restoring the acoustic information linked to the lexicon or to the context by the listener. The listener's degree of familiarity with the speaker or his pathology is also a source of variability. The bridging of the gap between speech production and perception by the interlocutor would be made possible by the use of a more suitable and automatic task. An acoustic-phonetic decoding test (or DAP in French, i.e. the production of isolated pseudo-words in repetition or reading), created within the framework of the InCA C2SI project, avoids the effects of cognitive restoration by the interlocutor. An automatic score from the DAP would lead to an overall score per patient, but also to scores specific to each phonetic segment, to be correlated with the analytical scores from each anatomical oropharyngeal segment. The study hypothesis is that the automatic processing of an acoustic-phonetic decoding task during the assessment in current practice is a valid and reliable tool for diagnosing oropharyngeal analytical and dynamic deficits by highlighting deficient linguistic units.

Interventions

OTHERAcoustic-phonetic decoding task (DAP)

Completion of speech-related quality of life autoquestionnaires Routine speech assessment Acoustic-phonetic decoding task (DAP) two lists of 16 pseudo-words

Sponsors

Laboratoire parole et langage
CollaboratorUNKNOWN
Laboratoire Information Avignon université
CollaboratorUNKNOWN
IRIT - Institut de Recherche en Informatique de Toulouse
CollaboratorUNKNOWN
University Hospital, Toulouse
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients aged at least 18 years old and benefiting from a social security scheme * Native French-speaking patients * Patients treated for cancer of the oral cavity or oropharynx (surgical and / or radiotherapy and / or chemotherapy treatment) * Patients in clinical remission for at least 6 months (chronic nature and stability of the disorders) * All tumor sizes according to the tumor (T), node (N), and metastasis (M) categories (TNM classification) (T1 to T4) * Patients with a perceptible speech disorder in a conversational situation or not (to allow the determination of fine deficits) * Patients who do not object to carrying out the research

Exclusion criteria

* Patients with an associated pathology potentially responsible for speech or fluency disorders (joint, speech and language disorders of developmental, organic or functional origin, voice disorders of organic or functional origin, stammering , stammering, fluency disturbances, speech disturbances of neurological origin) * Patients reporting an auditory complaint and not having a hearing aid * Inability to provide the person with enlightened information and to ensure the subject's compliance because of impaired physical and / or psychological health, * Patients participating in another research including an exclusion period still in progress.

Design outcomes

Primary

MeasureTime frameDescription
Correlation coefficientDay 1Correlation coefficient between he automatic score by phoneme class from the DAP and the score for each oropharyngeal anatomical segment from muscle testing

Secondary

MeasureTime frameDescription
Human perceptual score - Direct transcriptionDay 1the speech therapist will transcribe the pseudo-word he thinks he has recognized immediately after the subject says it, using software installed on the examination computer. A perceptual score of linguistic traits of average difference (between expected production and perception by the speech therapist) by phoneme will then be determined.
Human perceptual score - jury transcriptionDay 1Audio recordings of the task will be made. A perceptual score of linguistic traits of average difference (between expected production and perception by the jury) by phoneme will then be determined
Head and Neck Carcinologic Handicap Index (HNCHI)Day 1Correlation between HNCHI and scores from the DAP

Countries

France

Contacts

Primary ContactClémence DEVOUCOUX
devoucoux.c@chu-toulouse.fr06.50.72.24.85
Backup ContactAnaïs GALTIER
Galtier.a@chu-toulouse.fr05. 67. 77. 18 .70

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026