Droplet Spread, Healthy, Lung Infection, Respiratory Tract Infections
Conditions
Brief summary
Currently, a major issue within respiratory medicine is undertaking procedures that generate aerosolisation with the concern of spreading infection, such as the SARS-COV-2/COVID-19 virus. It is anecdotally reported that lung function testing and positive airways pressure devices used in clinical practice are aerosol generating procedures however the data to support this is limited. With the advent of high-speed imaging systems that can capture and quantify particle size and velocity we aim to investigate the aerosol generation in routine non-invasive positive pressure respiratory procedures.
Interventions
No interventions are implemented. This is an observational study of respiratory droplet aerosolisation during respiratory procedures.
Sponsors
Guy's and St Thomas' NHS Foundation Trust
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* Age 18-80 years * Healthy subjects with no active medical conditions or previous pneumothorax * Cognitively and linguistically able to follow instructions given in English and provide informed consent
Exclusion criteria
* Significant respiratory, cardiac or neurological conditions or previous pneumothorax * Smoking history greater than 10 pack years * Acute illness at the time of assessment * Allergies to latex, metals or local anaesthetic agents
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Characterisation of aerosolised respiratory droplets | 1 year | Performed using high-speed imaging and particle size counters |
Outcome results
None listed