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Blinded Resection in Case of the Pancreatic Insulinoma

Blinded Resection Avoided in Case of the Pancreatic Insulinoma

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04741152
Enrollment
197
Registered
2021-02-05
Start date
2010-01-31
Completion date
2020-12-31
Last updated
2021-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulinoma; Pancreas

Keywords

Insulinoma, Hypoglicemia, Blind resection, Hidden Insulinoma, ASVS

Brief summary

The blinded resection avoided in case of pancreatic insulinoma

Detailed description

Despite of the technique and technology developement there are still a lot of troubles to verify small benign-looking pancreatic NETs. It can be especially important in case of insulinoma. The organic hyperilsulinism and severe hypoglicemia causeb by the insulin/proinsulin - producing lesion can lead to severe complications and evem death. There are some cases of the blinded resections of the pancreas in patients with the hidden insulinoma when the tumor can't be revealed during the preoperative diagnostics and intraoperatively. Unfortunately, blind resection do not solve the problem of the hypoglicemia but also cause the specific pancreatic complications.

Interventions

Different pancreatic resections

Sponsors

Vishnevsky Center of Surgery
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

The blinded resection of the insulinoma

Exclusion criteria

Other tumors

Design outcomes

Primary

MeasureTime frameDescription
No hidden insulinomas2010 June - 2020 JuneTo improve the diagnostics of the tumor before and during the surgery. The hidden insulinomas haven't been diagnosed. The frozen section have to be routinely performed. The surgery haven't been finished before the morphologic confirmation of the resected lesion.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026