Skip to content

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04739189
Acronym
IDEX1
Enrollment
20
Registered
2021-02-04
Start date
2021-08-28
Completion date
2021-10-03
Last updated
2026-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Obesity

Keywords

appetite control, obesity, Adolescents, exercise, Energy Deficit

Brief summary

The aim of the present study is to compare the effect of iso-energetic energy deficits induced by exercise or dietary restriction on energy intake and appetite feelings in adolescents with obesity

Detailed description

The present study will compare the nutritional response to an energy deficit of 400 kcal induced once by realisation of an acute exercise set at moderate intensity and once by a dietary restriction imposed at lunch (compared with a control condition). 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (CON); ii) one session with an exercise-induced energy deficit (Def-EX); iii) one session with an energy restriction-induced energy deficit (Def-EI). Their ad libitum energy intake will be assessed during dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.

Interventions

BEHAVIORALCon : control condition without exercise / rest condition

Control condition without exercise / rest condition. The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at dinner time. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.

BEHAVIORALDef-EX : Condition with an exercise-induced energy deficit

Condition with an exercise-induced energy deficit The adolescents will be asked to complete an acute exercise set at 65% of their capacities (cycling) during the afternoon, inducing an energy expenditure of 400 kcal. Dinner will be served ad libitum. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.

BEHAVIORALDef-EI : Condition with an energy-restriction energy deficit

Condition with an energy-restriction energy deficit The adolescents will be asked to remain quiet during the whole day (no physical activity). They will receive a calibrated breakfast reduced from 400 kcal compare to their CON and Def-EX conditions. Dinner will be served ad libitum. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.

Sponsors

University Hospital, Clermont-Ferrand
Lead SponsorOTHER
Tza Nou - Maison médicale pour enfants et adolescentes
CollaboratorUNKNOWN
Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
CollaboratorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

* BMI percentile \> 97th percentile according to the french curves. * ages 12-16 years old * Signed consent form * being registered in the national social security system * no contraindication to physical activity

Exclusion criteria

* Previous surgical interventions that is considered as non-compatible with the study. * Diabetes * weight loss during the last 6 months * cardiovascular disease or risks

Design outcomes

Primary

MeasureTime frameDescription
Change from different intervention of energy intake measured during an ad libitum buffet meal (in kcal)day 1, day 8, day 15food intake will be measured ad libitum during a dinner buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software.

Secondary

MeasureTime frameDescription
Hunger feelingsday 1, day 8, day 15hunger area under the curve will be assessed using visual analogue scale through a the day
Food rewardday 1, day 8, day 15The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ)

Countries

France

Contacts

PRINCIPAL_INVESTIGATORValérie JULIAN

University Hospital, Clermont-Ferrand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 6, 2026