Pre-washing the Catheter With a Culture Medium Before Intrauterine Insemination

Does Pre-washing the Catheter With a Culture Medium Before Intrauterine Insemination Have an Effect on Pregnancy Rates?

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04736459

Enrollment

100

Registered

2021-02-03

Start date

2021-01-29

Completion date

2021-06-01

Last updated

2021-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

intrauterine insemination, pre-washing catheter

Brief summary

The aim of the study to evaluate the possible effect of washing the insemination catheters before intrauterine insemination on the pregnancy outcomes. We know that washing the catheters are already washed in the case of embryo transfer for assisted reproductive techniques. Based on this knowledge, we also constituted the hypothesis which is about the impact of washing the catheter on the gametes and embryos. The pre-washing the catheter before intrauterine insemination may provide higher pregnancy results.

Interventions

PROCEDUREPre-washed catheter vs. Unwashed catheter in the intrauterine insemination

The pre-washed catheter will be washed with culture medium before intrauterine insemination The unwashed catheter will not be washed with culture medium as a standard intrauterine insemination procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* at least 1-year infertility * at least one patent fallopian tube confirmed by hysterosalpingography (HSG) or laparoscopy * ovulatory menstrual cycles * suitable semen analysis according to the World Health Organization (WHO) criteria for intrauterine insemination

Exclusion criteria

* bilateral tubal occlusion * mild or severe endometriosis * day 3 serum FSH (follicle-stimulating hormone) \> 13 IU/L * abnormal thyroid function tests, hyperprolactinemia * total motile sperm count (TMSC) \< 5 millions or severe teratospermia (\<4% normal forms) following semen preparation * more than 3 follicles above the size of 17mm on the day of ovulation triggering

Design outcomes

Primary

Measure	Time frame	Description
Clinical pregnancy rate	8 weeks after intrauterine insemination	Clinical pregnancy will be defined as the presence of a heartbeat at 6th gestational weeks

Contacts

Primary ContactVehbi Yavuz Tokgöz

mdtokgoz@hotmail.com+902222392979

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026