Pediatric Obesity
Conditions
Keywords
appetite control, obesity, Adolescents, exercise, Energy Deficit
Brief summary
The aim of the present study is to compare the effect of iso-energetic energy deficits induced by energy restriction alone or exercise + dietary restriction (Mixed deficit) on energy intake and appetite feelings in adolescents with obesity.
Detailed description
The present study will compare the nutritional response to an energy deficit of 500 kcal induced once by dietary restriction alone and once by a mixed deficit (50% by exercise and 50% by dietary restriction) (compared with a control condition). 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (CON); ii) one session with a dietary-induced energy deficit (Def-EI); iii) one session with a mixed deficit (50% by exercise and 50% by dietary restriction) (Def-Mixed). Their ad libitum energy intake will be assessed at dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.
Interventions
Control condition without exercise / rest condition. The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at dinner time. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.
BEHAVIORALDef-Mixed. Condition with a mixed energy deficit induced by exercise + dietary restriction.
Def-Mixed. Condition with an exercise-induced energy deficit The adolescents will received a calibrated lundh meal with a deduction of 250 kcal compared with the lunch meal of Con; and will be asked to realise an acute exercise set at 65% of their capacities (cycling) during the afternoon, inducing an energy expenditure of 250 kcal. Dinner will be served ad libitum. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.
BEHAVIORALDef-EI. Condition with an energy-restriction energy deficit
Condition with an energy-restriction energy deficit The adolescents will receive a calibrated breakfast reduced from 500 kcal compare to their CON and Def-mixed conditions. Dinner will be served ad libitum. Their food reward will be assessed before dinner. Their appetite feelings will be assessed at regular intervals.
Sponsors
University Hospital, Clermont-Ferrand
Tza Nou - Maison médicale pour enfants et adolescentes
Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI percentile \> 97th percentile according to the french curves. * ages 12-16 years old * Signed consent form * being registered in the national social security system * no contraindication to physical activity
Exclusion criteria
* Previous surgical interventions that is considered as non-compatible with the study. * Diabetes * weight loss during the last 6 months * cardiovascular disease or risks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from different intervention of energy intake measured during an ad libitum buffet meal (in kcal). | day 1, day 8, day 15 | food intake will be measured ad libitum during a dinner buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger feelings | day 1, day 8, day 15 | hunger area under the curve will be assessed using visual analogue scale through a the day |
| Food reward | day 1, day 8, day 15 | The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ) (Finlayson, King et al. 2008). |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORValérie JULIAN
University Hospital, Clermont-Ferrand
Outcome results
None listed