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Methods of Confirmation of Brain Death

Use of Different Methods of Confirmation of Brain Death in Brain Death Donors

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04734574
Enrollment
60
Registered
2021-02-02
Start date
2022-04-01
Completion date
2023-12-30
Last updated
2023-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Death, Organ Donation

Brief summary

The purpose of this study is to describe the use of methods confirming brain death in the real clinical practice of the transplant program in the Czech Republic.

Detailed description

Organ donation is possible in the Czech Republic only after meeting the legislative requirements. These require confirmation of brain death by one of the statutory methods before organ harvesting. The use of these methods in clinical practice has not yet been described.The aim of this retrospective observational study is to describe the use of these methods in the real clinical practice of the transplant program in the Czech Republic, taking into account the legislation of other European countries.

Interventions

None listed

Sponsors

Brno University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* age ≥18 years * organ donor

Exclusion criteria

* age under 18 years

Design outcomes

Primary

MeasureTime frameDescription
Angiographywithin 24 hours after the onset of signs of brain deathCerebral panangiography
Brainstem auditory evoked potentialswithin 24 hours after the onset of signs of brain deathBrainstem auditory evoked potentials
Brain scintigraphywithin 24 hours after the onset of signs of brain deathBrain scintigraphy
Cerebral computed tomography angiographywithin 24 hours after the onset of signs of brain deathCerebral computed tomography angiography
Transcranial Doppler ultrasonographywithin 24 hours after the onset of signs of brain deathTranscranial Doppler ultrasonography

Countries

Czechia

Contacts

Primary ContactOndrej Hrdy, M.D.
hrdy.ondrej@fnbrno.cz532233850
Backup ContactJaroslav Duba, M.D.
duba.jarosalv@fnbrno.cz532233850

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026