ARDS, Pulmonary Perfusion
Conditions
Keywords
EIT, ARDS, pulmonary perfusion
Brief summary
This study is a clinical randomized controlled study.The objective of this study is to compare the prognosis of patients with ARDS between eit-v / q-oriented individualized ventilation strategy and traditional lung protection ventilation strategy, and to establish the demonstration application of eit-v / q-oriented ventilation strategy in ARDS
Interventions
PROCEDUREEIT-guided PEEP setting
Ventilator parameter setting by EIT
PROCEDUREARDS-net PEEP setting
Ventilator parameter setting according to ARDS-net table
Sponsors
Peking Union Medical College Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. According to ARDS Berlin standard, ARDS, PaO2 / FiO2 \< 200mmhg, peep \> 5cmh2o; 2. According to clinical judgment, lung recruitment therapy is needed due to hypoxemia; 3. The subjects or their families signed informed consent. 4. Admission to ICU was less than 72 hours; 5. The estimated duration of mechanical ventilation was more than or equal to 48 hours; 6. Age ≥ 18 years old and ≤ 80 years old;
Exclusion criteria
1. The patients with heart implants could not be monitored by EIT; 2. Patients or their families refused to participate in the study; 3. Hypernatremia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ventilation free days | 1 Day |
Secondary
| Measure | Time frame |
|---|---|
| 28-day mortality | 28 days |
Countries
China
Contacts
Primary ContactYun Long
Backup ContactSiyi Yuan
Outcome results
None listed