Sonographic Signs of Gouty Arthritis in Diagnosed and Suspected Patients
Conditions
Brief summary
The study is a cross sectional observational multicenter study. It is established in collaboration with the Egyptian college of rheumatology study group (ECRsg). It is conditioned that all the study participants had either mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal (MTP) joint in patients with a known history of gout or at high risk. Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjogren's syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis, seronegative spondyloarthropathy, will be excluded from the study. None of the participants had a history of intra-articular injection or aspiration in the scanned joints for 3 months prior to the inclusion in the study. The sonographers will be blinded for clinical data and the EULAR scanning protocol for the knee and 1st MTP will be considered \[2\]. Further, scanning of the double contour sign over the femur condyles anteriorly and posteriorly in sagittal planes will be assessed. All the sonographers in the study had an experience between 5 and 10 years in the field of musculoskeletal ultrasound.
Interventions
DIAGNOSTIC_TESTEvaluation of sonographic signs of gouty arthritis
the EULAR scanning protocol for the knee and 1st MTP will be considered \[2\]. Further, scanning of the double contour sign over the femur condyles anteriorly and posteriorly in sagittal planes will be assessed. Examination of erosions, tophus, double contour, effusion, and echogenic foci will be recorded.
Sponsors
Sohag University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal * patients with a known history of gout or at high risk
Exclusion criteria
* Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjoegren's syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis, seronegative spondyloarthropathy * History of intra-articular injection in the last 3 months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sonographic signs of gouty arthritis in the knee or 1st MTP joint | at baseline | Erosions, effusion, echogenic foci, and tophus using OMERACT definitions of sonographic signs of gouty arthritis |
Countries
Egypt
Outcome results
None listed