Sigmoid Cancer, Sigmoid Diverticulosis
Conditions
Keywords
LARS score, Sigmoidectomy, Sigmoid cancer, Diverticulitis, Functional results
Brief summary
The aim of this present study is to compare functional results and quality of life after sigmoidectomy for diverticulitis and sigmoid cancer.
Detailed description
Rectal resection surgery can lead to numerous complications in term of gastrointestinal results with onset of fecal incontinence or in contrast constipation, and in term of genitourinary results with occurrence of dysuria, erectile dysfunction, or vaginal dryness. The low anterior resection syndrome is defined by the occurrence after rectal resection, of gastrointestinal symptoms like fecal incontinence or stool evacuation difficulties, which affect quality of life, despite conservation of anal sphincter. This syndrome is now well known and used in many countries. However, there is a lack of data concerning gastrointestinal functional results after sigmoid surgery whether it is for cancer or diverticulitis. Some studies highlighted symptoms persistence in many patients after sigmoidectomy. Lately, the LARS score was used after sigmoidectomy for cancer. This study reveals symptoms of low anterior resection syndrome for 41 % of patients. The correlation between rectal resection and sigmoidectomy could be explain by the resection of the upper part of rectum in case of sigmoidectomy. The issue of genito-urinary disorders after sigmoidectomy are poorly researched. Previous studies demonstrate a higher risk of erectile disorders after pelvic surgery and especially for cancer. Currently, there is a lack of data on functional results and quality of life for patients who are going into sigmoid surgery, whether for cancer or diverticulitis. The aim of this longitudinal study is to compare digestive functional outcome, genitourinary outcomes and quality of life in patients who undergo sigmoid resection for diverticulitis and cancer.
Interventions
PROCEDURESigmoidectomy
The sigmoid resection surgery, realized by laparoscopy or laparotomy, with anastomosis.
Sponsors
Nantes University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
: * Adults * Patients who undergo sigmoidectomy with end to end anastomosis for sigmoid cancer and symptomatic diverticulitis * Preservation of the left colic angle for upper surgical resection * Lower surgical resection located \< 5cm to the recto-sigmoid junction
Exclusion criteria
: * Minors * Adults under guardianship * Protected persons * Patients who undergo sigmoidectomy without anastomosis (ileostomy or Hartmann surgery) * Patients who undergo surgery in emergency * Cancer of recto-sigmoid junction * Patients who undergo secondarily a stoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| LARS score | At the visit of preoperative | To measure incontinence troubles after low anterior resection. The score is from 0 to 42. The higher the score, the worst the incontinence. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| GIQLI | At the visit of preoperative | Quality of life related to gastrointestinal symptoms. Score from 0 to 144. The higher the score, the better the quality of life. |
| SF-36 | At the visit of preoperative | General quality of life score. Described with 8 scaled scores, which are : vitality, physical functioning, bodily pain, general health perceptions, physical role functioning, social role functioning, mental health. Each scale score is from 0 to 100. The higher the score the less disability. |
| FSFI | At the visit of preoperative | Measure of sexual functioning in women. Score from 0 to 95. The higher the score, the better the sexual function. |
| Bristol stool chart | At the visit of preoperative | A scale to classify the form of the stools in seven category which indicate constipation or diarrhea in function of the type. Types 1 and 2 indicate constipation, types 3 and 4 are normal stools, type 5, 6 and 7 indicate diarrhea. |
| IPSS | At the visit of preoperative | Questionary to screen and manage symptoms of benign prostatic hyperplasia. Score from 0 to 35. The higher the score, the worst the urinary function. |
| IIEF5 | At the visit of preoperative | Questionary about erection problems on patient's sex life. Score from 1 to 25. The higher the score, the better the sexual function. |
| ICIQ-FLUTS | At the visit of preoperative | Questionary for evaluating female lower urinary tract symptoms and impact on quality of life. Score from 0 to 48. The higher the score, the worst the urinary continence. |
Countries
France
Contacts
Primary ContactEmilie DUCHALAIS-DASSONNEVILLE, PH
Outcome results
None listed