Epilepsy
Conditions
Keywords
Epilepsy, Peidatrics, Positron emission tomography (PET)
Brief summary
This retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with epilepsy.
Detailed description
This retrospective study aimed to develop a new approach for automatic localization of epilepsy foci in children with intractable epilepsy. Pediatric patients with intractable epilepsy would be retrospectively included in this study. The inclusion criteria included (1) age between 6 and 18 y; (2) detailed seizure semiology evaluation, MRI, EEG and interictal 18F-FDG PET/CT examination; (3) clinical diagnosis as focal epilepsy. The exclusion criteria included (a) any history of central nervous system disease; (b) poor image quality due to head movement.
Interventions
RADIATION18F-FDG
All subjects received 18F-FDG PET examination.
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* 1\. age between 6 and 18 years. * 2\. detailed presurgical evaluation, including seizure semiology evaluation, MRI, EEG and interictal 18F-FDG PET/Computer Tomography (CT) examination. * 3\. clinical diagnosis as focal epilepsy.
Exclusion criteria
* 1\. any history of central nervous system (CNS) disease such as trauma and CNS tumor. * 2\. poor image quality due to head movement.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy | Through study completion, about 6 months | The accuracy of epilepsy focus localization. |
| Kappa | Through study completion, about 6 months | The agreement between experiment result and clinical diagnosis. |
Countries
China
Outcome results
None listed