Healthy Adults
Conditions
Brief summary
This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.
Interventions
DIAGNOSTIC_TESTReal-Time Myocardial Echocardiography (RTMPE)
Uses sound waves (ultrasound) to produce an images of the heart. During RTMPE a microbubble contrast agent is administered through an intravenous line (IV) to make the images of your heart clearer.
DIAGNOSTIC_TESTMagnetic resonance image (MRI)
Imaging that focuses on the heart or blood vessels to assess size and function of the heart's chambers, thickness and movement of the walls of the heart, and blood flow in the blood vessels.
Sponsors
Mayo Clinic
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 18 years. * Available for testing performed in Rochester, MN. * Willing to undergo both an echocardiogram with RTMPE and CMR. * Study subject providing consent.
Exclusion criteria
* Adults \< 18 years. * BMI \<30 kg/m\^2. * Hypertension. * Diabetes Mellitus. * Stroke. * Cardiomyopathy or structural heart disease. * Known coronary artery disease or history of myocardial infarction. * Contraindication to echo enhancement agent or gadolinium administration such as an allergy. * Renal GFR \< 50 mL/mL. * Females who are pregnant. * Subject unwilling to consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Myocardial blood volume | Baseline | Ratio in systole and diastole (MBVs/MBVd) by real-time myocardial perfusion echocardiography (RTMPE) |
Countries
United States
Outcome results
None listed