Intense Pulsed Light, Erbium-yttrium Aluminum Garnet Laser, Scar Prevention
Conditions
Brief summary
The scar site was divided into 3 sites; combined IPL/fractional Er:YAG laser treatment site, fractional Er:YAG laser treatment site and untreated control site. At baseline, three lesions were randomized to IPL / fractional Er:YAG laser combination therapy site, fractional Er:YAG laser treatment alone site, and untreated control site. The laser treatment was conducted total three sessions, immediately at suture removal (baseline), 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment (20 weeks after suture removal).
Interventions
DEVICEfractional Er:YAG laser
At baseline, three lesions were randomized. Topical anesthetic cream was applied to the scar 30 minutes before laser treatment. The same dermatologist performed 2,940 nm Er:YAG fractional laser. (long pulse mode, 1500mJ, 2Hz, 2 pass) The face was cooled after treatment with gauze soaked in ice water. The laser treatment was conducted total three sessions, immediately at suture removal, 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment.
DEVICEIntense pulse light
At baseline, three lesions were randomized. Topical anesthetic cream was applied to the scar 30 minutes before laser treatment. The same dermatologist performed IPL. (irridation energy: 12.5J/cm2, pulse duration: 10ms, 1pass) The face was cooled after treatment with gauze soaked in ice water. The laser treatment was conducted total three sessions, immediately at suture removal, 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment.
Sponsors
Hallym University Kangnam Sacred Heart Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of postoperative scars on the abdomen * scars were symmetrical shaped in a line of 3cm or more
Exclusion criteria
* uncontrolled systemic or chronic disease * hypersensitive to the ingredients * a history of other laser treatments within the past 6 months * pregnancy * lactation * Recent sun exposure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient Observer Scar Assessment Scale | 4 weeks | The POSAS observer consists of following 6 items: vascularity, pigmentation, thickness, surface area, relief, pliability. Each item was evaluated on a scale from 1 (normal skin) to 10 (worst scar). Finally, the POSAS total score was calculated as the sum of six items, ranging from 6 to 60. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total Vancouver Scar scale | 4 weeks | The VSS consists of 4 following components: vascularity, pigmentation, height ranging from 0 to 3, and pliability from 0 to 5. Score zero means the normal skin, while maximum scores indicate the worst scar. |
| Erythema index | 4 weeks | The indexes were measured by placing Spectrophotometer (Cortex Technology, Had- sund, Denmark) directly on the skin lesions for two minutes in the room with constant temperature (20\ 24 degree Celsius) and humidity (28\ 38 percent). This measurement was performed to determine erythema. |
| Melanin index | 4 weeks | The indexes were measured by placing Spectrophotometer (Cortex Technology, Had- sund, Denmark) directly on the skin lesions for two minutes in the room with constant temperature (20\ 24 degree Celsius) and humidity (28\ 38 percent). This measurement was performed to determine pigmentation. |
Countries
South Korea
Contacts
Primary ContactBo Young Chung, M.D., PhD
Outcome results
None listed