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Pulmonary Tuberculosis Sequelae in Patients With COPD

Effects of Pulmonary Tuberculosis Sequelae on Functional Outcomes in Patients With COPD

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04721080
Enrollment
150
Registered
2021-01-22
Start date
2020-05-01
Completion date
2021-05-01
Last updated
2021-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Copd, Quality of Life, Tuberculosis

Keywords

copd, tuberculosis, exercise capacity, quality of life

Brief summary

It is known that there is a complex relationship between tuberculosis and COPD. Post-tuberculosis airway disease or COPD associated with tuberculosis occurs in a significant portion of tuberculosis patients. However, it was observed that mortality rates and exacerbation rates of COPD patients with tuberculosis sequel were higher. However, the effect of tuberculosis sequela on functional outcomes in COPD patients has not been investigated in the studies. The aim of this study is to determine whether the previous tuberculosis sequelae has a functional effect on patients with COPD.

Detailed description

This research is planned as a cross-sectional study. It will start within one week following the approval of the ethics committee and will be completed within one year. The universe of the study is S.B.Ü. Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital consists of patients who apply to Pulmonary Rehabilitation Outpatient Clinic. Participants will consist of two different groups: COPD patients with tuberculosis and COPD patients without tuberculosis. The voluntary principle will be taken into account in participating in the research. Within the scope of the evaluation; Demographic and clinical information of the people who will participate in the study will be recorded, and Thorax CT and PFT examinations performed within the polyclinic service within the last 1 month will be evaluated. Saint George Respiratory Questionaire (SGRQ), 6-minute walk test (6MWT), Medical Research Council Dyspnea Scale (MRC), COPD assessment test (CAT) will be applied to the patients. Regarding the illness histories, the number of hospitalizations and emergency admissions in the last 1 year will be recorded. Detailed tuberculosis anamneses will also be taken from patients with tuberculosis sequelae.

Interventions

OTHERFunctional Outcome Measurements

Dyspnea Exercise capacity Quality of life assessment

Sponsors

Izmir Katip Celebi University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Volunteering to participate in the study * Being over 18 years old * Having thorax CT in the last 1 month * Having PFT examination performed in the last 1 month

Exclusion criteria

* Being in a COPD attack * The patient has additional pulmonary comorbidity such as Lung Ca, bronchiectasis, lung fibrosis.

Design outcomes

Primary

MeasureTime frameDescription
Exercise Capacity6 minutes- baselineSix minutes walk test

Secondary

MeasureTime frameDescription
Dyspnea Assessment5 minutes- baselineMedical Research Council Scale(MRC)
COPD Assessment5 minutes- baselineCOPD Assessment Test (CAT
Quality of Life Assessment20 minutes- baselineSt. George Respiratory Questionaire

Countries

Turkey (Türkiye)

Contacts

Primary Contactİlknur N Gürşan, Assoc Prof
ilknurnaz4@gmail.com05356954634

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026