Epidural Anesthesia, General Anesthesia
Conditions
Keywords
headache, blood pressure
Brief summary
Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with 12mlof 0.25% bupivacaine and 1% lignocaine plain whereas in group G all patients underwent surgery under general anesthesia. Intra-operative heart rate, mean arterial pressure (MAP) and post operative opioid consumption in first 24hrs were recorded as primary outcomes whereas presence or absence of respiratory complication and duration of hospital stay as secondary outcome.
Interventions
DRUGThoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine)
patients in epidural anesthesia were given epidural anesthesia and assessed for heart rate and mean arterial pressure
DRUGgeneral anesthesia effect on heart rate in Laparoscopic Cholecystectomy
patients in general anesthesia were given epidural anesthesia and assessed for heart rate and mean arterial pressure
Sponsors
Armed Forces Hospital, Pakistan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Intervention model description
one group to be studied for effects of epidural anesthesia and other group for effects of general anesthesia
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
1. patients having ASA statusI-III 2. age more than 18 years, 3. both genders 4. planned to undergo laparoscopic cholecystectomy
Exclusion criteria
1. Patients who did not give consent, 2. Allergic to local anesthetic 3. Hemodynamically unstable, 4. Pregnant, full stomach patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effectiveness of thoracic epidural anesthesia with general anesthesia for Laparoscopic cholecystectomy in terms of change in heart rate during surgery in immediate 24 hours-heart rate. | changes in heart rate at 24 hours of surgery. | the efficacy of thoracic epidural anesthesia was compared with general anesthesia for laproscopic cholecystectomy in the immediate post operative period in terms of intra operative heart rate. |
| effectiveness of thoracic epidural anesthesia with general anesthesia for Laparoscopic cholecystectomy in terms of change in mean arterial blood pressure during surgery in immediate 24 hours-mean arterial blood pressure. | changes in mean arterial pressure at 24 hours of surgery | efficacy of thoracic epidural anesthesia was compared with general anesthesia for laproscopic cholecystectomy in the immediate post operative period in terms of mean arterial blood pressure intra operatively and in immediate post operative period |
Countries
Pakistan
Outcome results
None listed