Multiple Sclerosis
Conditions
Brief summary
The aim of the present study is to evaluate the effects of training performed with the LUNA-EMG system to enhance motor functions of the lower limb in multiple sclerosis. This is a randomized open-label trial. Patients will be randomized into the intervention group (LUNA-EMG, 30-45 minutes once a week for 12 weeks) or in the control group (standard care). The effect of the training will be measured based on the muscular strength, walking tests, proprioception and a quality of life questionnaire.
Interventions
DEVICELUNA-EMG
The LUNA-EMG (Samcom) system is a robot that allows the evaluation of muscular strength through the recording of muscle activity (electromyography - EMG) in order to provide precise objective data on the patient's muscle function. In addition to the diagnostic aspect (evaluation of muscle strength, range of motion and proprioception), the LUNA-EMG robot provides optimized range of motion's movements and a visual feedback on the patient's performance. In addition, it may enhance neuroplasticity due to the increased number of movements repetitions which could influence motor learning.
Sponsors
University of Liege
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* EDSS less or equal to 6.5 * Between 18 and 70 years old * Having signed the informed consent
Exclusion criteria
* Acute pain syndrome * Severe cognitive deficits * Risk of fracture or unconsolidated fracture * Rigid joints (spasticity, severe osteoarthritis and arthritis) or unstable joints * Severe ataxia and apraxia * Epilepsy * Pacemakers and similar implants * Insufficient skin conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle strength in mV | 12 weeks | Muscular strength is measured with a dynamometer. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proprioception | 12 weeks | Patients proprioception will be measured with the LUNA system. It calculates the distance in degree (°) between the target arm position and the arm position that the patient try to reproduce. Lower degree represent a more accurate positioning of the arm by the patient. |
| Timed 25-Foot Walk, seconds | 12 weeks | The patient is directed to one end of a clearly marked 25-foot course and is instructed to walk 25 feet as quickly as possible, but safely. The faster the better. |
| Timed Up and Go, seconds | 12 weeks | The person must get up from the seated position and walk three meters away from the chair and then retrace their steps (turn 180 degrees) and sit down again. The faster the better. |
Countries
Belgium
Outcome results
None listed