Pain, Postoperative, Craniotomy, Adverse Effect, Anxiety
Conditions
Keywords
postoperative pain, neurosurgery, craniotomy, anxiety
Brief summary
Postoperative pain after craniotomy is frequent, with moderate-severe intensity. The fear to the side effects of opioids (nausea and vomiting and sedation), and NSAIDs (bleeding) makes it difficult to obtain adequate analgesic control in these patients. Preoperative anxiety may be associated with a poorer postoperative analgesic control, hindering the adequate postoperative evolution and increasing hospital stay and adverse effects. In this observational study, the investigators aimed to assess the postoperative analgesic management in patients undergoing scheduled craniotomy following routine clinical practice and to relate preoperative anxiety with the postoperative analgesic evaluation in this population.
Detailed description
Postoperative pain after craniotomy is frequent, with moderate-severe intensity. The fear to the side effects of opioids (nausea and vomiting and sedation), and NSAIDs (bleeding) makes it difficult to obtain adequate analgesic control in these patients. On the other hand, preoperative anxiety may be associated with a poorer postoperative analgesic control and hinder the adequate postoperative evolution. The main outcome is to assess the postoperative analgesic management in patients undergoing to craniotomy. Secondary objectives are to evaluate the appearance of postoperative side effects related to the analgesics and to assess the relationship between preoperative anxiety and postoperative pain
Interventions
DRUGMetamizole
Patients will receive metamizole intraoperatively and throughout 48h postoperatively.
Sponsors
Dr. Negrin University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 18 years old undergoing scheduled form for supratentorial craniotomy. * Signed informed consent.
Exclusion criteria
* Mini Mental State Examination with a score less than or equal to 24 points. * Patients suffering from disabilities. * Patients who can not collaborate in the postoperative clinical assessment. * Patients who can not be assessed during the postoperative period by the Acute Pain Unit.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | 48 hours postoperatively | Using the Visual Analgesic Scale (from 0 to 10, with 0 being the state corresponding to no pain and 10 being the maximum pain imaginable ) and postoperative analgesic satisfaction assessed by the patient (stratified in Bad, Fair, Good or Excellent). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Side effects secondary to metamizol | 48 hours postoperatively | Rate of appearance of postoperative side effects. |
| To assess the correlation between preoperative anxiety and postoperative pain. | From the day before surgery to the second day postoperatively | Relate the score obtained in the State Anxiety Inventory Trait (STAI) (from 0 to 60) with the intensity of postoperative pain (from 0 to 10). |
Countries
Spain
Outcome results
None listed