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The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance

The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04719975
Enrollment
25
Registered
2021-01-22
Start date
2021-02-01
Completion date
2021-07-31
Last updated
2021-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroencephalography, Mental Fatigue

Brief summary

The purpose of this project is to provide further insights into the neurophysiology behind the MF-induced impairment in endurance performance. The aim is to perform a randomized controlled trial in which we partly replicate studies of Marcora et al. (2009) and Bigliassi et al. (2017), while extensively monitoring brain activity during the entire protocol (i.e. both cognitive and physical tasks) by using EEG.

Interventions

A modified Stroop task of approximately 60 min will be used in order to induce mental fatigue (MF). This will be based on their performance during the max test that was conducted during the familiarization session. In this task, which will be partitioned in 4 blocks of 468 stimuli, four colored words (rood, blauw, groen and geel) will be presented one at a time on a computer screen. The participants will be required to indicate the color of the word, ignoring the meaning of the word itself.

In the control task subjects will have to watch a documentary of 60 min on the same computer screen as the one used for the experimental trial. In order to avoid under- and over-arousal the subjects will have the opportunity to choose between several documentaries as proposed by the research team. During the control task physiological and psychological measures will be assessed at the same time points as during the mental fatigue trial.

Sponsors

Vrije Universiteit Brussel
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Randomized, blinded, counter-balanced, cross-over design

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy (No neurological or cardiovascular disorders) * Male or female * No medication * Non-smoker * Between 18 and 35 years old * Recreational athlete population (performance level 2 or 3 for men according to De Pauw et al. (2013) and performance level 2 or 3 for woman according to Decroix et al. (2016)

Exclusion criteria

* Injuries over the last 6 months * Suffering from any cardiovascular condition * Use of medication * Suffering from other health conditions at the time of testing * Use of caffeine or alcohol 24 hours prior to each trial * Heavy efforts 24 hours prior to each trial

Design outcomes

Primary

MeasureTime frameDescription
Electroencephalogram data1 hours 30 minutes - 2 hoursDuring whole of the trials EEG data will be gathered, each trial will last one and a half to two hours. EEG power in delta, theta, alpha, beta band.
Reaction Time Flanker TaskTotal of 10 minutesReaction Time will be assessed during Flanker task
Accuracy Flanker TaskTotal of 10 minutesAccuracy will be assessed during Flanker task
Reaction Time Stroop Task60 minutesReaction Time will be assessed during Stroop task
Accuracy performance Stroop Task60 minutesAccuracy will be assessed during Stroop task

Countries

Belgium

Contacts

Primary ContactMatthias Proost, MSc
matthias.proost@vub.be026292753

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026