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Epidemiology of Abnormal Vaginal Discharge During Pregnancy

Epidemiology and Clinico-investigative Study of Abnormal Vaginal Discharge During Pregnancy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04719754
Enrollment
164
Registered
2021-01-22
Start date
2021-06-01
Completion date
2022-12-31
Last updated
2021-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal Infection

Brief summary

Vaginitis among women of childbearing age is well acknowledged as a public health concern due to its high occurrence. Vulvovaginitis is a disorder of the vulva and/or vagina caused by infection, inflammation, or changes in the flora. There are many types of infections that affect the vagina, the most common three types of infection: bacterial vaginosis, trichomoniasis, and candidiasis. Bacterial vaginosis is the most common vaginal infection in women of reproductive age causing thin and milky vaginal discharge with a fishy odor. Trichomoniasis causes a frothy, greenish-yellow discharge with a foul smell. Vaginal Candidiasis is one of the most common fungal infections of the female genital tract and the second most common vaginal infection affecting women of reproductive age (after the bacterial infection worldwide. It affects more than 75% of women at least once in their lifetime, with approximately 50% of them also suffering a single recurrence. About 75% of patients suffering from candidiasis are asymptomatic, but it may be symptomatic with clinical picture characterized by itching, vaginal pain, vulvar burning sensation, dyspareunia, dysuria and mildly unpleasant odor, erythema and vulvar edema, white-yellowish plaques on the walls of the vagina and cervix and cheesy vaginal discharge. The risk of vulvo-vaginal candidiasis increases by 30% during pregnancy also in pregnancy, the presence of vaginitis is related to abortion, intrauterine infection, fetal growth retardation, premature rupture of membranes, preterm birth, low birth weight, puerperal infection, and other adverse pregnancy outcomes.

Interventions

DIAGNOSTIC_TESTVaginal swab

The other vaginal swab will be cultured on blood agar, chocolate agar, MacConkey agar and Sabourauds dextrose agar. The cultures will be incubated at 37ºC for 24-96 h or until the colonies appear.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
19 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* At any gestational age * Age of patient: 19-40

Exclusion criteria

* Women in labor * Women with current vaginal bleeding * Women with current preterm rupture of membrane * Women immunocompromised women * Women patients who refused to participate in the study

Design outcomes

Primary

MeasureTime frame
The prevalence of microorganism in the vaginal discharge during pregnancy.9 months

Countries

Egypt

Contacts

Primary ContactDoaa Makarem, MSc
Doaamakarem5@gmail.com+201065312287
Backup ContactAhmed Alaa Youssef, MD
ahmedalaa11282@yahoo.com01006184921

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026