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Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case Report

Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case Report

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04713423
Enrollment
1
Registered
2021-01-19
Start date
2017-10-19
Completion date
2017-10-19
Last updated
2021-01-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes Simplex Virus Infection

Keywords

Herpetic gingivostomatitis, Herpes simplex virus, Perioral lesions, Infants, Case report, Herpes simplex virus type 1, Oral lesions

Brief summary

A five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles.

Detailed description

The investigators present the case of a five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles. The investigators discuss the pathophysiology of primary herpes simplex virus infection and the effect of maternal antibodies on the infant's immune system. In addition, the investigators explain the diagnosis, management, and prognosis of herpes simplex virus infection in young infants.

Interventions

DIAGNOSTIC_TESTDiagnosis and treatment of the case

The infant was transferred to a hospital for better management of her infection. She was immediately started on intravenous acyclovir (20 mg/kg/6 h/5 d) while acetaminophen suppositories (80 mg/8 h/5 d) were given to lower her body temperature. In addition, other palliative drugs, such as diphenhydramine syrup (12.5 mg/5 mL, 2.5 mL orally) once-a-night for five days, were given to ease the effort of drinking and to aid in achieving good sleep. Upon completion of five days of therapy, the patient showed complete recovery and was subsequently discharged from the hospital free from symptoms.

Sponsors

Princess Nourah Bint Abdulrahman University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
OTHER

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* Five-months-old infants or younger

Exclusion criteria

* Six-months-old infants or older

Design outcomes

Primary

MeasureTime frameDescription
Health conditionone weekNumber of tests were performed and different drugs were administered

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026