Intracerebral Haemorrhage, Subarachnoid Haemorrhagic Stroke, Traumatic Brain Injury
Conditions
Keywords
Consciousness, Coma, Recovery, Electroencephalogram
Brief summary
The purpose of this research study to find out if clinically unconscious acute brain injury patients that show brain activation to music and language on electroencephalogram (EEG) (bedside test) have better outcomes and wake up in the future.
Interventions
DIAGNOSTIC_TESTAuditory stimuli
Auditory stimuli (passive, active perturbations)
Sponsors
University of Miami
National Institutes of Health (NIH)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
For ABI Participants * ABI adult (18 years and older) patients who are admitted to the intensive care unit * Unconscious with Glasgow Coma Scale (GCS) \<8 on presentation and unable to follow bedside commands. * A negative COVID-19 test on arrival For Healthy Volunteers: * 18 years and older
Exclusion criteria
For All Participants: * \<18 years of age * Pregnant woman * Patients with cardiac arrest on presentation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glasgow Outcome Scale-Extended (GOSE) Scale | Up to 5 years | The GOSE is an outcome scale, range 1-8 evaluating the patients' functional outcomes - higher score indicates better recovery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Coma Recovery Scale - Revised (CRS-R) | Up to 5 years | The CRS-R will evaluate the patients' conscious state, range 0-23 -higher score indicates a better conscious state |
Countries
United States
Contacts
CONTACTAyham Alkhachroum, MD
PRINCIPAL_INVESTIGATORAyham Alkhachroum, MD
University of Miami
Outcome results
None listed