Anesthesia
Conditions
Brief summary
The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and sevoflurane with laryngeal mask airway for endoscopic ureteral lithotripsy.
Detailed description
This is a randomized controlled trial. There were 60 cases of endoscopic ureteral lithotripsy under general anesthesia with laryngeal mask airway were enrolled. All cases were randomly divided into two group (desflurane or sevoflurane). Each group had 30 cases. Primary outcome was time to awakening. Secondary outcomes were time to wash-out of volatile anesthetics, time to extubation, irritation after awakening, and modified Aldrete score. Statistical analysis was performed by using Kaplan-Meieir curve and log-rank test for time to adequate depth of anesthesia and time to awakening; t-test for time to wash-out of volatile anesthetics; chi-square test for depth of anesthesia by PRST score, irritation after awakening and Aldrete score; Fisher test for adverse effects of volatile anesthetics. The research was approved by Gia Dinh People Hospital ethics committee
Interventions
OTHEROther
Compare time to awakening and quality of recovery after general anesthesia between two groups.
Sponsors
Gia Dinh People Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* All eligible subjects who underwent endoscopic ureteral lithotripsy under general anesthesia * ASA I and II
Exclusion criteria
* Contraindication to laryngeal mask airway. * Indication for conversion to tracheal intubation during surgery. * History of malignant hyperthermia. * Pregnancy. * Obese (BMI \>25 kg/m2). * Substances abuse.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to awakening | After stopping volatile anesthetics to patient awakening, up to 30 minutes. | Time required for awakening |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to wash-out of volatile anesthetics | After stopping volatile anesthetics to complete wash-out of volatile anesthetics, up to 30 minutes | Time required for washing out volatile anesthetics |
| Time to extubation | After stopping volatile anesthetics to readiness for extubation, up to 30 minutes | Time required for successful extubation. |
| Irritation after awakening | After awakening to eligible discharge, up to 2 hours. | Aono score \>2 |
| Adverse effects of volatile anesthetics | After providing volatile anesthetics until they were stopped, up to 90 minutes | Hypotension, cough, nausea and vomitting. |
Countries
Vietnam
Outcome results
None listed