Recurrent S. Aureus Infections in Osteoarticular Infections

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04712123

Acronym

RELAPSTAPH

Enrollment

Registered

2021-01-15

Start date

2021-08-01

Completion date

2023-01-01

Last updated

2022-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone and Joint Infection, Staphylococcus Aureus Infection

Keywords

Staphylococcus Aureus Infection, Bone and Joint Infection, relapse

Brief summary

Staphylococcus aureus osteoarticular infections, in particular those associated with the presence of implant, relapse in 20% of cases. Currently, the reasons for these relapses are poorly understood, whether on the microbiological or clinical side. The aim of this study is to improve knowledge on persistence of mechanisms of S. aureus

Interventions

OTHERrelapse due to S. aureus

to find out if it is the same S. aureus in both infections

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients having had an osteoarticular infection with or without material due to S. aureus presenting a recurrence of S. aureus infection

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
rate of patients having had an osteoarticular infection due to S. aureus	between 2015 and 2020	proportion of patients having had an osteoarticular infection due to S. aureus
Description of patients having had an osteoarticular infection due to S. aureus	between 2015 and 2020	type of patients: age, BMI, comorbidities...
Description of Bone and Joint Iinfection/Prosthesis Joint Infection	between 2015 and 2020	implant or prosthesis or not, acute/ chronic, bacteriology

Secondary

Measure	Time frame	Description
rate of patients having had a relapse due to persistence of S. aureus	between 2015 and 2020	proportion of patients having had an osteoarticular infection due persistence of S. aureus
rate of S. aureus strain identical between the initial episode and the relapse	between 2015 and 2020	proportion of relapse due to the same strain of S. aureus than in the initial episode

Countries

France

Contacts

Primary ContactEugenie Mabrut, CRA

eugenie.mabrut@chu-lyon.fr04 26 73 29 38

Backup ContactTristan Ferry, MD,PhD

tristan.ferry@chu-lyon.fr04 26 73 29 38

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026