Short-term Perioperative Thromboprophylaxis After Major Abdominal Surgery

Outcomes of Short-term Perioperative Thromboprophylaxis After Gastrointestinal Cancer Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04709510

Enrollment

Registered

2021-01-14

Start date

2019-01-01

Completion date

2020-08-31

Last updated

2021-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep Vein Thrombosis

Keywords

deep vein thrombosis, short-term thromboprophylaxis

Brief summary

Major abdominal surgery for cancer is major risk factor for thromboembolism. Patients who undergo major abdominal surgery are prone to develop venous thromboembolism, both in the early postoperative period and after hospital discharger. There are strong recommendations in the international guidelines in favor to pharmacological thromboprophylaxis. Thus there is no consensus dor the duration of the prophylaxis. There are authors that suggest extended prophylaxis up to 4 week after surgery. On the other hand, there are prospective randomized trials that inpatient (short-term up to 7-10 days) prophylaxis is adequate.

Detailed description

This is a retrospective cohort study with 89 patients who underwent major abdominal surgery for colorectal and gastric cancer. All patients received short term prophylaxis (during hospital stay only) rather than extended prophylaxis (4 weeks). All participants received duplex ultrasound in the study period for the diagnosis of deep vein thrombosis.

Interventions

DIAGNOSTIC_TESTDuplex Ultrasound

Duplex Ultrasound was performed for every participants for the diagnosis of symptomatic or asymptomatic deep vein thrombosis

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Intervention model description

Retrospective Cohort

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Older than 18 * Major abdominal surgery gor colorectal or gastric cancer * Caprini Risk score less than 9 * No history of anticoagulant treatment * Thromboprophylaxis during hospital stay only

Exclusion criteria

* Younger than 18 * Caprini Risk score 9 and above * History of anticogulants * Not reachable by phone etc

Design outcomes

Primary

Measure	Time frame	Description
The incidence of thromboembolic events by radiological assessment	3 years follow up	All patients in the cohort received short time prophylaxis for deep vein thrombosis instead of prolonged duration. All patients will be assessed with ultrasound.

Secondary

Measure	Time frame	Description
Rate of predisposing factors of the patients	3 years follow up	The patients with deep vein thrombosis in the cohort will be assessed according to their postoperative period features, histories, chemo treatments etc. with and questionnaire.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026