Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04709120

Acronym

ACTIV-2

Enrollment

2968

Registered

2021-01-14

Start date

2020-10-01

Completion date

2021-05-30

Last updated

2023-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation, CKD, Comorbidities and Coexisting Conditions, COPD, Covid19, Death, Diabetes, DVT, Risk Factor, Cardiovascular

Keywords

Covid19, Comorbidities and Coexisting Conditions, Risk Factor, SARS-CoV-2, COVID-19 Second Wave, COVD-19 First Wave, Death

Brief summary

Comparison of COVID-19 disease course in hospitalized patients infected by SARS-CoV-2 in first and second waves of the novel coronavirus infection

Detailed description

Non-commercial depersonalized multi-centered registry study on analysis of chronic non-infectious diseases dynamics after SARS-CoV-2 in first and second waves of the novel coronavirus infection in cohort of Russian adult patients. Retrospective analysis of medical histories and outcomes in adults with pre-existing conditions after SARS-CoV-2 infection. Comorbidities worsening risk factors measuring through evaluation of range of indicators such as dynamics of diabetes, CKD, COPD, bronchial astma, incidence of hypertonic crises, vascular events and others.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

Suspected or confirmed COVID-19 (according to results of swab-test, antibody test, computed tomography or radiography image)

Exclusion criteria

1. Unwillingness to participate in the study; 2. Age under 18.

Design outcomes

Primary

Measure	Time frame	Description
death	4 weeks	death for any reason

Secondary

Measure	Time frame	Description
Number of cases of Myocarditis and Acute Coronary Events depending on Coexisting Conditions	4 weeks	Number of cases of Myocarditis and Acute Coronary Events depending on Coexisting Conditions
Number of cases of Cytokine Storm depending on Coexisting Conditions	4 weeks	Number of cases of Cytokine Storm depending on Coexisting Conditions
Number of cases of Acute Kidney Injury depending on Coexisting Conditions	4 weeks	Number of cases of Acute Kidney Injury depending on Coexisting Conditions
Decline in GFR excluding Acute Kidney Injury by the time of discharge depending on Coexisting Conditions	4 weeks	Decline in GFR excluding Acute Kidney Injury by the time of discharge depending on Coexisting Conditions
Rate of cases of health status worsening occured during hospitalisation	4 weeks	Rate of cases of health status worsening occured during hospitalisation
Number of thrombotic and thromboembolic complications of COVID-19 depending on Coexisting Conditions	4 weeks	Number of thrombotic and thromboembolic complications of COVID-19 depending on Coexisting Conditions

Countries

Russia

Outcome results