Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis

Exercise Capacity in Axial Spondyloarthritis and Factors Affecting it: a Cross-sectional Controlled Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04706650

Enrollment

Registered

2021-01-13

Start date

2014-05-15

Completion date

2014-10-15

Last updated

2021-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Axial Spondyloarthritis, Exercise Capacity

Keywords

axial spondyloarthritis, exercise capacity, cardiovascular risk factors, nonradiographic axial spondyloarthritis, cardiorespiratory fitness

Brief summary

The investigators aimed to study the associations between exercise capacity and cardiovascular (CV) risk factors in axial spondyloarthritis (axSpA) patients and to determine possible relationships with disease-related variables. Thirty eight patients and 38 controls were recruited in our cross-sectional controlled study. Comprehensive systemic and musculoskeletal examinations were carried out in both of the groups. Cardiovascular risk profile data, ASDAS-CRP, 10-year CV event risk, physical activity levels (IPAQ) were recorded. A maximal treadmill exercise test by Bruce protocol was administered to all participants.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* clinical diagnosis of axial SpA * must be able to walk

Exclusion criteria

* established cardiac disease including structural heart diseases, * uncontrolled hypertension, * cardiac rhythm disorder, * unstable angina pectoris, * chronical renal and/or hepatic disease, * malignancy, * neuromuscular disease * musculoskeletal deformity * the history of an inflammatory arthritis for control group

Design outcomes

Primary

Measure	Time frame	Description
Mean difference in exercise capacity of axSpA patients and controls	may- october 2014	maximal METs achieved by a maximal treadmill test by Bruce protocol

Secondary

Measure	Time frame	Description
Mean difference in heart rate recovery of axSpA patients and controls	may- october 2014	peak heart rate achieved by maximal exercise minus heart rate at 1st minute of recovery phase

Outcome results