Glioma, Postoperative Motor Deficit
Conditions
Brief summary
This study focused on glioma patients with postoperative motor deficits, especially for patients with supplementary motor area syndrome. The investigators want to investigate whether the recovery of motor function will be accelerated by using transcranial magnetic stimulation to stimulate primary motor area and supplementary motor area on the lesional hemisphere.
Interventions
DEVICETMS treatment
Using TMS to stimulate (5 Hz, 90%\ 110% resting motor threshold) patients' primary motor area and SMA.
Sponsors
Beijing Neurosurgical Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
patients with postoperative motor deficits, especially for patients with SMA syndrome.
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. patient underwent awake craniotomy and motor functional identification during tumor resection; 2. patients with postoperative motor deficit (muscle strength of limbs is weaker than preoperative status)
Exclusion criteria
1. patients with contraindication of transcranial magnetic stimulation; 2. patients without data of the pre- and postoperative resting state MRI and diffusion tensor image.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accelerate motor functional recovery | From the day of tumor resection to 3 months after tumor resection. | The ratio of motor functional recovery in patients with TMS treatment is higher than those do not receive TMS treatment and the time of motor funcitonal recovery is shorter than those do not receive. |
Countries
China
Contacts
Primary ContactShengyu Fang, MD
Backup ContactYinyan Wang, MD
Outcome results
None listed