Large Acquired Nevi, Multiple Nevi, Nevus, Skin Lesion
Conditions
Keywords
Atypical Skin Lesions, Skin Lesions, Multiple Nevi, Large Acquired Nevi, Memorial Sloan Kettering Cancer Center, 20-010
Brief summary
The purpose of this study is to find out whether the Nevisense device can provide useful information about atypical moles to complement the usual assessments done during routine screening for melanoma. Assessing particpants' moles with the Nevisense device may help improve screening methods for the early detection of melanoma in people with atypical mole syndrome.
Interventions
DIAGNOSTIC_TESTNevisense electrical impedance spectroscopy
Each participants will undergo Nevisense electrical impedance spectroscopy in order to characterize the electrical impedance spectroscopy scores of nevi in patients with ≥ 100 nevi on the entire cutaneous surface and at least three large acquired nevi (LAN) \> 5 mm in diameter
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients (\> 30 years of age) at the time of the initial study visit. * Patients displaying a phenotype that consists of ≥ 100 nevi on the entire cutaneous surface and at least three large acquired nevi (LAN) \> 5 mm in diameter. These patients have atypical mole syndrome, which is a high-risk nevus phenotype and the target patient population in this study. * Patients with at least three clinically stable nevi between 5 and 20 mm in diameter. * Patients (or LAR) who are able to provide informed consent. * Patients with previous total body photography images taken at least 3 years prior
Exclusion criteria
* Patients without at least three clinically stable nevi between 5 and 20 mm in diameter. * Patients with any electronic implantable devices. * Patients who are pregnant (verbally confirmed with the participant).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Electrical impedance spectroscopy scores of participants' nevi | 2 weeks | The primary objective is to characterize the electrical impedance spectroscopy scores of nevi in patients with ≥ 100 nevi on the entire cutaneous surface and at least three large acquired nevi (LAN) \> 5 mm in diameter. |
Countries
United States
Outcome results
None listed