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Artificial Intelligence and Postoperative Acute Kidney Injury

Development and Prospective Validation of an Artificial Intelligence Model to Predict Postoperative Acute Kidney Injury

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04705064
Enrollment
2000
Registered
2021-01-12
Start date
2021-03-01
Completion date
2022-02-01
Last updated
2021-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-cardiac Surgery

Keywords

Artificial Intelligence, Postoperative acute kidney injury, Prospective validation

Brief summary

The main objective of this study is to develop and validate an artificial intelligence model that predicts postoperative acute kidney injury.

Detailed description

Postoperative acute kidney injury is known to increase the length of hospital stay and healthcare cost. A lot of risk prediction models have been developed for identifying patients at increased risk of postoperative acute kidney injury. Recent advances in artificial intelligence make it possible to manage and analyze big data. Prediction model using an artificial intelligence and large-scale data can improve the accuracy of prediction performance. Furthermore, the use of an artificial intelligence may be a useful adjuvant tool in making clinical decisions or real-time prediction if it is integrated into the electrical medical record systems. However, before implementing an artificial intelligence model into the clinical setting, prospective evaluation of an artificial intelligence model's real performance is essential. However, to our knowledge, there was no artificial intelligence model for prediction of postoperative acute kidney injury, which was prospectively evaluated. Therefore, we aimed to develop an artificial intelligence model which predicts postoperative acute kidney injury and evaluate the model's performance prospectively.

Interventions

DIAGNOSTIC_TESTPrediction of postoperative acute kidney injury using an artificial intelligence

The performance of an artificial intelligence model to predict postoperative acute kidney injury will be tested prospectively.

Sponsors

Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Adults patients undergoing non-cardiac surgery

Exclusion criteria

* Age under 18 years * Surgery duration \< 1 hour * Transplantation surgery * Nephrectomy * Cardiac surgery * Patients who had severe kidney dysfunction preoperatively as follows: * Serum creatinine ≥ 4 mg/dl * Estimated glomerular filtration rate \<15 ml/min/1.73m2 * History of renal replacement therapy * Patients who had no results of preoperative or postoperative serum creatinine

Design outcomes

Primary

MeasureTime frameDescription
the incidence of postoperative acute kidney injuryduring the postoperative seven dayspostoperative acute kidney injury (diagnosed by KDIGO criteria using peak serum creatinine level) included all acute kidney injury events regardless of acute kidney injury severity

Countries

South Korea

Contacts

Primary ContactHyung-Chul Lee, MD.PhD
vital@snu.ac.kr+821024566336

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026