Coronary Heart Disease
Conditions
Brief summary
Investigators evaluated the efficacy of a pilot-tested mHealth intervention to improving medication adherence and health outcomes among patients with coronary heart disease.
Detailed description
This was a two-arm parallel randomized controlled trial, in which 116 and 114 participants were assigned to the experimental and control groups, respectively. The mHealth intervention in this study had been pilot tested and tailored. Specifically, the experimental group received a medication-taking reminder every morning via WeChat app and educational materials of coronary heart disease and medication adherence every five days via Message Express app. The control group received only general educational materials, which were irrelevant to coronary heart disease or medication adherence, every 5 days via Message Express app. All participants were diagnosed with coronary heart disease. The specific recruitment criteria of participants had been published in peer-reviewed journal.
Interventions
BEHAVIORALMedication-taking reminders & educational materials
The intervention has been described in arm/group descriptions, which lasted for 60 days for each participants.
BEHAVIORALEducational materials
The intervention has been described in arm/group descriptions, which lasted for 60 days for each participants.
Sponsors
West China Hospital
Duke University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* (1) had a medical diagnosis of coronary heart disease; * (2) aged 18 years or older; * (3) had an antihypertensive medication regimen for 90 days or more from enrollment; * (4) able to read messages through mobile phone; * (5) had a mobile phone that could receive messages from WeChat and reminders from Message Express; * (6) capable of giving his/her own consent; and * (7) had an electronic blood pressure cuff to check blood pressures and heart rates.
Exclusion criteria
* was enrolled in other research studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of medication non-adherence | Participants' medication non-adherence scores were measured at enrollment (baseline), 15-day, 30-day, 45-day, 60-day (end of intervention), 75-day, and 90-day (end of follow-up) | Participants' medication non-adherence scores were measured using the Voils Medication Non-Adherence Extent Scale. Specifically, participants received the question items of the Voils Medication Non-Adherence Extent Scale every 15 days on WeChat app and provided answers |
| Change of systolic blood pressure | At enrollment (baseline), 15-day, 30-day, 45-day, 60-day (end of intervention), 75-day, and 90-day (end of follow-up) | Participants self-measured their systolic blood pressures every 15 days using a blood pressure cuff and reported them to investigators |
| Change of diastolic blood pressure | At enrollment (baseline), 15-day, 30-day, 45-day, 60-day (end of intervention), 75-day, and 90-day (end of follow-up) | Participants self-measured their diastolic blood pressures every 15 days using a blood pressure cuff and reported them to investigators |
| Change of heart rate | At enrollment (baseline), 15-day, 30-day, 45-day, 60-day (end of intervention), 75-day, and 90-day (end of follow-up) | Participants self-measured their heart rates every 15 days using a blood pressure cuff and reported them to investigators |
Countries
China
Outcome results
None listed