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Comparison of Ocular Findings in Patients Between Surgical and Natural Menopause

Comparison of Ocular Findings in Patients Between Surgical and Natural Menopause

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04703231
Enrollment
60
Registered
2021-01-11
Start date
2020-09-01
Completion date
2022-03-23
Last updated
2022-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macula Edema, Menopause Surgical, Visual Acuity Reduced Transiently

Keywords

menopause, Eye disease, Macular changes

Brief summary

It is aimed to compare the ocular findings in patients with natural and surgical menopause.

Detailed description

To compare the parameters such as fundus examination, macular thickness, visual acuity and lens opacities among female patients diagnosed with menopause between the ages of 40-65.The criteria for exclusion from the study are the presence of a history of illness, drug use, smoking and alcohol use.Inclusion criteria were female patients who were in menopause and who did not use any medications. For surgical menopause, the uterus and ovaries were surgically removed at least 3 months ago.

Interventions

DIAGNOSTIC_TESTmeasurement of macular thickness, corneal thickness and lens opacities

The incidence of macular thickness, Corneal thickness, intraocular pressure and lens opacities will be investigated by an ophthalmologist.

Sponsors

Batman Training and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
45 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Newly diagnosed menopause (Natural or Surgical Menopause( At least 3 months after surgery), * No history of illness(Diabetes,Heart disease,Kidney disease etc.) * Not Smoking * Did not use alcohol * Have not use any medication * Age between 45-65 years * BMI between 20-25 kg/m

Exclusion criteria

* Smoking or Alchohol consumption * Age before 45 and after 65 years * Have chronic disease * Using any medication * Have not diagnosed Menopause * BMI greater than 30 kg/m

Design outcomes

Primary

MeasureTime frameDescription
Macular thickness measurement3 months after menopauseMacular thickness(micron) in both eyes will be measured by optical coherence tomography,
Detecting lens opacities3 months after menopauseLens opacities (Grade 1,2,3,4) will be measured by indirect biomicroscopy,
Intraocular pressure measurement3 months after menopauseIntraocular pressures( mm Hg) will be measured and recorded with the applanation tonometry device.
Comparison of all detected data3 months after menopauseAll numerical data will be analyzed and compared with relevant statistical tests and the p value will be accepted as less than 0.05 to be considered a statistically significant difference.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026