Percutaneous Coronary Intervention Patients
Conditions
Keywords
Viscosity, Contrast, Nephropathy, Coronary Intervention
Brief summary
In our study, we aimed to investigate how whole blood viscosity (WBV) affects the development of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI).
Detailed description
In our study, 500 patients who applied to the cardiology clinic and underwent PCI for elective procedure, ST segment elevation myocardial infarction (STEMI), and non-STEMI were prospectively included. Before the procedure, we calculated WBV using the formula \[(0.12 × hematocrit) + (0.17 × (total protein - 2.07)\]. We defined CIN as the absolute (≥0.5 mg/dl) or relative increase (≥25%) in serum creatinine 48-72 h after exposure to a contrast agent compared with baseline serum creatinine values.
Interventions
OTHERBlood Viscosity Testing
we calculated WBV using the formula \[(0.12 × hematocrit) + (0.17 × (total protein - 2.07)\]. We defined CIN as the absolute (≥0.5 mg/dl) or relative increase (≥25%) in serum creatinine 48-72 h after exposure to a contrast agent compared with baseline serum creatinine values.
Sponsors
Bursa Postgraduate Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* patients between ages 18 and 90 * underwent PCI in our hospital between
Exclusion criteria
* Patients with chronic kidney disease (CKD) who underwent hemodialysis or peritoneal dialysis * Patients who underwent to coronary bypass surgery within 48 h were excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Contrast Induced Nephropathy | 48 to 72 hours | CIN was defined as an increase in serum creatinine levels greater than 0.5 mg/dl or 25% or more increase compared to basal serum creatinine levels 48 to 72 h after exposure. |
Countries
Turkey (Türkiye)
Outcome results
None listed